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4-히드록시-템포

4-히드록시-템포 구조식 이미지

카스 번호:: 2226-96-2

한글명:: 4-히드록시-템포

동의어(한글):: 4-히드록시-템포;사메틸피페리딘올N-옥실;4-하이드록시-2,2,6,6-테트라메틸피페리딘-1-옥실;사메틸피페리딘올N-옥실(TETRAMETHYLPIPERIDINOLN-OXYL);1-피페리딘일옥시, 4-하이드록시-2,2,6,6-테트라메틸-;4-옥시피페리돌;4-하이드록시-2,2,6,6-테트라메틸-1-피페리딘일옥시;4-하이드록시-2,2,6,6-테트라메틸피페리딘-N-옥실;나이트록실-2;피페리딘, 4-하이드록시-2,2,6,6-테트라메틸-1-옥시-;피페리딘옥시, 4-하이드록시-2,2,6,6-테트라메틸-

상품명:: 4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy

동의어(영문):: TEMPOL;4-OH-TEMPO;4-HYDROXY-TEMPO;Inhibitor 701;ZJ-701;TMPN;HYDROXY-TEMPO;Polymerization inhibitor 701;Tetramethylpiperidinol N-oxyl;4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl

CBNumber:: CB5782374

분자식:: C9H18NO2*

포뮬러 무게:: 172.24

MOL 파일:: 2226-96-2.mol

속성

안전

MSDS

용도

공급 업체 540

4-히드록시-템포 속성

녹는점: 69-71 °C(lit.)

끓는 점: 302.58°C (rough estimate)

밀도: 1.0402 (rough estimate)

증기압: 0.025Pa at 20℃

굴절률: 1.4350 (estimate)

인화점: 146°(295°F)

저장 조건: 2-8°C

용해도: 1670g/l

물리적 상태: 결정 또는 결정성 분말

산도 계수 (pKa): 5.07[at 20 ℃]

색상: 오렌지 레드

색상: 오렌지색

수소이온지수(pH): 8.2 (20g/l, H2O, 20℃)

수용성: 녹는

Merck: 14,9141

BRN: 1422990

안정성: 안정적인. 강한 산화제와 호환되지 않습니다.

InChIKey: FAPCFNWEPHTUQK-UHFFFAOYSA-N

LogP: 0.56 at 25℃

CAS 데이터베이스: 2226-96-2(CAS DataBase Reference)

NIST: 1-Piperidinyloxy, 4-hydroxy-2,2,6,6-tetramethyl-(2226-96-2)

EPA: 1-Piperidinyloxy, 4-hydroxy-2,2,6,6-tetramethyl- (2226-96-2)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xn,Xi
위험 카페고리 넘버	22-36/37/38-36/38
안전지침서	26-36-37/39-36/37/39-27
WGK 독일	1
RTECS 번호	TN8991000
TSCA	Yes
HS 번호	29333999
유해 물질 데이터	2226-96-2(Hazardous Substances Data)
독성	LD50 oral in rat: 1053mg/kg
기존화학 물질	KE-20899

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501
H318	눈에 심한 손상을 일으킴	심한 눈 손상 또는 자극성 물질	구분 1	위험		P280, P305+P351+P338, P310

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P312	삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	1
3		0

4-히드록시-템포 MSDS

2,2,6,6-Tetramethyl freeagaoxy-4-piperidyl

4-히드록시-템포 C화학적 특성, 용도, 생산

개요

TEMPOL is a piperidine nitroxide and spin label with superoxide dismutase (SOD) mimetic activity. It inhibits lipid peroxidation in rat liver microsomes with 50% inhibition of microsomal lipid peroxidation (IP₅₀) values of 117, 61, and 381 μM for peroxidation induced by iron plus NADPH, iron plus ascorbate, and t-butylhydroperoxide, respectively. TEMPOL (1 mM) inhibits production of superoxide anions by 92% via a xanthine-xanthine oxidase reaction in vitro. It reduces mean arterial pressure and heart rate in spontaneously hypertensive rats (ED₅₀s = 70 and 63 μmol/kg, respectively) when administered intravenously. TEMPOL is a cell-permeable spin label that has been used to quantify intracellular oxygen in various cell types by electron spin resonance (ESR) spectroscopy.

화학적 성질

solid

용도

A free radical scavenger

주요 응용

In biochemical research, 4-hydroxy-TEMPO has been investigated as an agent for limiting reactive oxygen species. It catalyzes the disproportionation of superoxide, facilitates hydrogen peroxide metabolism, and inhibits Fenton chemistry.4-Hydroxy-TEMPO, along with related nitroxides, are being studied for their potential antioxidant properties.On an industrial-scale 4-hydroxy-TEMPO is often present as a structural element in hindered amine light stabilizers, which are commonly used stabilizers in plastics, it is also used as a polymerisation inhibitor, particularly during the purification of styrene.

일반 설명

4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic.

생물학적 활성

Superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects.

4-히드록시-템포 준비 용품 및 원자재

원자재

준비 용품

6-Hydroxy-2-naphthaldehyde 비스(2,2,6,6-테트라메틸-1-피페리다이닐옥시-4-일) 세바케이트

4-히드록시-템포 공급 업체

글로벌( 540)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Jiangxi Lotchem Co.,Ltd.	+8615270827708	lancetu@jxlotchem.com	CHINA	338	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58
ZHEJIANG ESTCHEM CO.,LTD	15957180504	sales@zjestchem.com	China	193	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Dalian Richfortune Chemicals Co., Ltd	0411-84820922 8613904096939	sales@richfortunechem.com	China	303	57
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60

4-히드록시-템포 관련 검색:

할로페리돌 2,2,6,6-사메틸-4-피페리디놀 2,2,6,6-사메틸-4-(메틸설포닐 옥시)-1-피페리디노 옥시, 자유 라디칼 4-히드록시-템포 벤조산염,라디칼 4-히드록시-템포 CHLOROPHOSPHONAZO III 1,2,2,6,6-Pentamethyl-4-piperidinol Drag-reduction agent Triacetonediamine 2,2,6,6-Tetramethylpiperidine Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-oxide 9,10-Dihydro-10-(2,3-dicarboxypropyl)-9-oxa-10-phosphaphenanthrene 10-oxide Octabenzone Piperazine-2-carboxylic acid dihydrochloride Tri(4-isopropylphenyl) phosphate 3-Hydroxyphenylphosphinyl-propanoic acid Triphenyl phosphate