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1-도코사놀

1-도코사놀
1-도코사놀 구조식 이미지
카스 번호:
661-19-8
한글명:
1-도코사놀
동의어(한글):
1-도코사놀;베헤닐알코올
상품명:
n-Docosanol
동의어(영문):
ik2;lidavol;tadenan;JARCOL 22;DOCOSANOL;Emery 3304;ALCOHOL C22;1-DOCOSANOL;N-DOCOSANOL;Docosan-1-ol
CBNumber:
CB6219657
분자식:
C22H46O
포뮬러 무게:
326.6
MOL 파일:
661-19-8.mol

1-도코사놀 속성

녹는점
65-72 °C(lit.)
끓는 점
180 °C0.22 mm Hg(lit.)
밀도
d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml
굴절률
n75 1.4360
저장 조건
Store below +30°C.
산도 계수 (pKa)
15.20±0.10(Predicted)
물리적 상태
Pellets or Tablets
색상
White
수용성
Insoluble
Merck
13,3433
BRN
1770470
안정성
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS 데이터베이스
661-19-8(CAS DataBase Reference)
NIST
1-Docosanol(661-19-8)
EPA
1-Docosanol (661-19-8)

안전

안전지침서 24/25
WGK 독일 -
RTECS 번호 JR1315000
TSCA Yes
HS 번호 29051900
유해 물질 데이터 661-19-8(Hazardous Substances Data)
독성 LD50 intraperitoneal in mouse: > 800mg/kg
기존화학 물질 KE-12789

1-도코사놀 MSDS


1-Docosanol

1-도코사놀 C화학적 특성, 용도, 생산

화학적 성질

1-DOCOSANOL is white powder

용도

antiviral

용도

n-Docosanol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants.

정의

1-DOCOSANOL is a  long-chain, saturated fatty alcohol.

Indications

Docosanol (Abreva) is a long-chain saturated alcohol that is clinically effective against HSV. It has in vitro activity against many enveloped viruses, including CMV, influenzavirus, and respiratory syncytial virus.
Docosanol is not directly virucidal; instead, it blocks the entry of the virion into the host cell by inhibiting the fusion of the viral envelope with the host plasma membrane. Because it does not affect viral replication or protein production, it may be less susceptible to the development of resistance than other antiviral drugs.

Pharmaceutical Applications

1-DOCOSANOL is a 22-carbon straight chain alcohol licensed for over-thecounter sales for the topical treatment of herpes labialis. It is thought to act by blocking viral fusion with the host cell, although definitive studies are lacking. The clinical relevance of the antiviral activity has been debated and the place of this medication as a treatment of herpes labialis remains to be established.

Clinical Use

Docosanol cream is approved for the over-the-counter treatment of herpes labialis. It shortens the duration of symptoms of cold sores and fever blisters but does not provide symptomatic relief.

부작용

Adverse effects of docosanol are minimal. Skin irritation occurs infrequently. Drug interactions are not anticipated.

Purification Methods

Crystallise docosanol from ether or chloroform/ether. [Beilstein 1 IV 1906.]

1-도코사놀 준비 용품 및 원자재

원자재

준비 용품


1-도코사놀 공급 업체

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Henan Tianfu Chemical Co.,Ltd.
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career henan chemical co
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Chongqing Chemdad Co., Ltd
+86-13650506873
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Target Molecule Corp
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marketing@targetmol.com United States 19232 58
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