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n-Docosanol

n-Docosanol
n-Docosanol structure
CAS No.
661-19-8
Chemical Name:
n-Docosanol
Synonyms
ik2;lidavol;tadenan;JARCOL 22;DOCOSANOL;Emery 3304;ALCOHOL C22;N-DOCOSANOL;N-DOCOSANOL;1-DOCOSANOL
CBNumber:
CB6219657
Molecular Formula:
C22H46O
Formula Weight:
326.6
MOL File:
661-19-8.mol

n-Docosanol Properties

Melting point:
65-72 °C(lit.)
Boiling point:
180 °C0.22 mm Hg(lit.)
Density 
d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml
refractive index 
n75 1.4360
storage temp. 
2-8°C
form 
Pellets or Tablets
pka
15.20±0.10(Predicted)
color 
White
Water Solubility 
Insoluble
Merck 
13,3433
BRN 
1770470
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
661-19-8(CAS DataBase Reference)
EWG's Food Scores
1
NIST Chemistry Reference
1-Docosanol(661-19-8)
EPA Substance Registry System
1-Docosanol (661-19-8)
SAFETY
  • Risk and Safety Statements
Safety Statements  24/25
WGK Germany  -
RTECS  JR1315000
TSCA  Yes
HS Code  29051900
Toxicity LD50 intraperitoneal in mouse: > 800mg/kg

n-Docosanol price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.22047 1-Docosanol 1-Docosanol for synthesis. CAS 661-19-8, molar mass 326.6 g/mol., for synthesis 661-19-8 8220470100 $53.6 2019-12-02 Buy
Sigma-Aldrich 169102 1-Docosanol 98% 661-19-8 50g $61 2019-12-02 Buy
TCI Chemical D0964 1-Docosanol >98.0%(GC) 661-19-8 25g $38 2019-12-02 Buy
TCI Chemical D0964 1-Docosanol >98.0%(GC) 661-19-8 500g $207 2019-12-02 Buy
Cayman Chemical 23793 Docosanol ≥98% 661-19-8 50g $29 2018-11-19 Buy

n-Docosanol Chemical Properties,Uses,Production

Chemical Properties

1-DOCOSANOL is white powder

Uses

antiviral

Uses

n-Docosanol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants.

Definition

1-DOCOSANOL is a  long-chain, saturated fatty alcohol.

Indications

Docosanol (Abreva) is a long-chain saturated alcohol that is clinically effective against HSV. It has in vitro activity against many enveloped viruses, including CMV, influenzavirus, and respiratory syncytial virus.
Docosanol is not directly virucidal; instead, it blocks the entry of the virion into the host cell by inhibiting the fusion of the viral envelope with the host plasma membrane. Because it does not affect viral replication or protein production, it may be less susceptible to the development of resistance than other antiviral drugs.

Pharmaceutical Applications

1-DOCOSANOL is a 22-carbon straight chain alcohol licensed for over-thecounter sales for the topical treatment of herpes labialis. It is thought to act by blocking viral fusion with the host cell, although definitive studies are lacking. The clinical relevance of the antiviral activity has been debated and the place of this medication as a treatment of herpes labialis remains to be established.

Clinical Use

Docosanol cream is approved for the over-the-counter treatment of herpes labialis. It shortens the duration of symptoms of cold sores and fever blisters but does not provide symptomatic relief.

Side effects

Adverse effects of docosanol are minimal. Skin irritation occurs infrequently. Drug interactions are not anticipated.

Purification Methods

Crystallise docosanol from ether or chloroform/ether. [Beilstein 1 IV 1906.]

n-Docosanol Preparation Products And Raw materials

Raw materials

Preparation Products


n-Docosanol Suppliers

Global( 160)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22631 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1892 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30053 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23978 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8734 58
Kono Chem Co., Ltd
+86-132 8924 6953(Whatsapp/Wechat)
+86-29-86107037 info@konochemical.com CHINA 2995 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35438 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 127809 58
Mainchem Co., Ltd. +86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32445 55

View Lastest Price from n-Docosanol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-14 1-Docosanol
661-19-8
US $1.00 / KG 1KG 98% 1ton career henan chemical co

n-Docosanol Spectrum


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