CAY10650

CAY10650 구조식 이미지
카스 번호:
1233706-88-1
상품명:
CAY10650
동의어(영문):
CS-1520;CAY10650;CAY10650, >=98%;CAY 10650;CAY-10650;CAY10650;CAY-10650;CAY 10650;3-isobutanoyl-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]indole-5-carboxylic acid;3-isobutyryl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)-1H-indole-5-carboxylic acid;3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid;1H-Indole-5-carboxylic acid, 3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-;acanthamoeba,inhibit,CAY 10650,PGE2,CAY10650,lipid droplets,neutrophils,keratitis,mannose-induced protein,corneal epithelial cells,CAY-10650,Inhibitor,Phospholipase
CBNumber:
CB62590453
분자식:
C28H25NO6
포뮬러 무게:
471.5
MOL 파일:
1233706-88-1.mol

CAY10650 속성

녹는점
103-104℃
끓는 점
685.4±55.0 °C(Predicted)
밀도
1.24±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
산도 계수 (pKa)
4.03±0.30(Predicted)
물리적 상태
가루

안전

CAY10650 C화학적 특성, 용도, 생산

개요

Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process. CAY10650 is a highly potent (IC50 = 12 nM) cPLA2α inhibitor. It demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis. The phase I metabolite of this compound, CAY10641 , is also available.

CAY10650 준비 용품 및 원자재

원자재

준비 용품


CAY10650 공급 업체

글로벌( 61)공급 업체
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ATK CHEMICAL COMPANY LIMITED
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Jilin Chinese Academy of Sciences-yanshen Technology
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Aladdin Scientific
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Amadis Chemical Company Limited
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sales@amadischem.com China 131981 58
Haoyuan Chemexpress Co., Ltd. 021-58950125
info@chemexpress.com China 7553 61
AdooQ BioScience, LLC +1 (866) 930-6790
info@adooq.com United States 2784 58

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