RO-32-0432
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RO-32-0432 속성
- 끓는 점
- 712.2±60.0 °C(Predicted)
- 밀도
- 1.32±0.1 g/cm3(Predicted)
- 저장 조건
- −20°C
- 용해도
- DMSO: 용해될 수 있다
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 7.91±0.60(Predicted)
- 색상
- 오렌지 레드
- 색상
- 오렌지색
안전
| WGK 독일 | 3 | ||
|---|---|---|---|
| HS 번호 | 3822000000 |
RO-32-0432 C화학적 특성, 용도, 생산
용도
Bisindolylmaleimide XI is a potent and selective cell-permeable protein kinase C (PKC) inhibitor. Studies reveal that inhibition of PKCα by Bisindolylmaleimide XI and other similar PKC inhibitors has been associated with enhanced cardiac contractility and protection from heart failure. Bisindolylmaleimide XI has been shown to prevent T-cell activation and proliferation associated with chronic infl ammatory responses in vivo.생물학적 활성
Selective cell-permeable protein kinase C inhibitor. Displays slight selectivity for conventional PKC isoforms over Ca 2+ and atypical PKC isoforms; binding affinities for rat isoforms are 9, 28, 31, 37 and 108 nM for PKC's α , β Ι, β ΙΙ, γ and ε respectively. Orally available and prevents T-cell chronic inflammation in vivo .RO-32-0432 준비 용품 및 원자재
원자재
준비 용품
RO-32-0432 공급 업체
글로벌( 53)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Jinan Ruisi Pharmaceutical Technology Co., LTD | 0531-69900633 18340090523 |
changyuan20@163.com | China | 1717 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24131 | 58 |
| ApexBio Technology | -- |
sales@apexbt.com | United States | 6254 | 58 |