ChemicalBook
Chinese English Japanese Germany Korea

ANANDAMIDE

ANANDAMIDE 구조식 이미지
카스 번호:
94421-68-8
상품명:
ANANDAMIDE
동의어(영문):
AEA;ANANDAMIDE;anandamide(20.4,n-6);ARACHIDONYLETHANOLAMIDE;ARACHIDONOYL ETHANOLAMIDE;N-ARACHIDONOYLETHANOLAMINE;Anandamide(inTocrisolveTM100);Anandamide (in Tocrisolve 100);n-(2-hydroxyethyl)anachidonamide;n-arachidonoyl-2-hydroxyethylamide
CBNumber:
CB7168648
분자식:
C22H37NO2
포뮬러 무게:
347.53
MOL 파일:
94421-68-8.mol

ANANDAMIDE 속성

밀도
0.92 g/mL at 25 °C(lit.)
인화점
14 °C
저장 조건
−20°C
용해도
ethanol: soluble
물리적 상태
oil
색상
light yellow

안전

위험품 표기 F
위험 카페고리 넘버 11
안전지침서 24/25-16-7
유엔번호(UN No.) UN 1170 3/PG 2
WGK 독일 3
RTECS 번호 JX3842500

ANANDAMIDE C화학적 특성, 용도, 생산

정의

ChEBI: An N-(polyunsaturated fatty acyl)ethanolamine resulting from the formal condensation of carboxy group of arachidonic acid with amino group of ethanolamine.

위험도

A reproductive hazard.

생물학적 활성

Endogenous cannabinoid and vanilloid receptor agonist, in water-soluble emulsion (for details see TocrisolveTM 100). K i values are 89 and 371 nM for CB 1 and CB 2 receptors respectively; EC 50 values are 18, 31 and 27 nM at GPR55, CB 1 and CB 2 respectively; pK i = 5.68 for rVR1. Also blocks TNF- α -induced NF-kB activation via direct inhibition of IKK. Also available as the pure oil dissolved in ethanol (N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide ).

효소 저해제

This lipid neurotransmitter and endocannabinoid receptor ligand (FW = 347.54 g/mol; CAS 94421-68-8), also known as arachidonylethanolamide, inhibits calcium ion currents and activates the MAP kinase signaling pathway. Anandamide is a naturally occurring effector of central and peripheral nervous systems, as mediated by CB1 and CB2 cannabinoid receptors, respectively. (These receptors were originally characterized as binding Δ9 -tetrahydrocannabinol, or THC, marijuana’s major psychoactive ingredient.) Anandamide, 2-arachidonoylglycerol, and congeners (N- oleoylethanolamide and N-palmitoylethanolamide) are lipophilic signalling molecules with multiple physiological roles in learning and memory, neuroinflammation, oxidative stress, neuroprotection and neurogenesis. Anandamide likewise plays a role in regulating uterine implantation of the early-stage embryo (blastocyst). Anandamide synthesis occurs from N- acetylphosphatidylethanolamine by multiple pathways that include phospholipase A2, phospholipase C, and NAPE-hydrolyzing phospholipase D (or NAPE-PLD). Target(s): adenylate cyclase; Na + channels; a7-nicotinic acetylcholine receptor; 5 HT3 receptors; Ca 2+ channels; K+ channels, voltage-gated; acylglycerol lipase, or monoacylglycerol lipase.

ANANDAMIDE 준비 용품 및 원자재

원자재

준비 용품


ANANDAMIDE 공급 업체

글로벌( 37)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15881 69
Ascent Scientific 4401179829988
4402030 700 369 customerservice@ascentscientific.co.uk United Kingdom 279 60
Chemfun Medical Technology(Shanghai) Co., Ltd. 021-67220633 & 021-37212706
+86-21-67220638 chemfun@chemfun.net China 21812 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@163.com China 300 58
Syntechem Co.,Ltd Please Email
E-Mail Inquiry info@syntechem.com China 13010 57
ChemStrong Scientific Co.,Ltd 0755 66853366
0755 28363542 sales@chem-strong.com; China 15615 56
Shanghai Kewel Chemical Co., Ltd. +86 (21) 6460-9169
+86 (21) 6460-9160 kewelchemexp@yahoo.com China 9834 50
Chizhou Kailong Import and Export Trade Co., Ltd. Please Email
- xg01_gj@163.com China 9562 50

Copyright 2019 © ChemicalBook. All rights reserved