브로모나이트로메테인
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브로모나이트로메테인 속성
- 녹는점
- -28 °C
- 끓는 점
- 146-148 °C/750 mmHg (lit.)
- 밀도
- 2.007 g/mL at 25 °C (lit.)
- 굴절률
- 1.485-1.495
- 인화점
- 4°C
- 용해도
- Chloroform (Soluble), DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Slig
- 산도 계수 (pKa)
- 7.22±0.29(Predicted)
- 물리적 상태
- 액체
- 색상
- 맑은 노란색
- 안정성
- 감광성, 휘발성
- CAS 데이터베이스
- 563-70-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn-O,Xi,O | ||
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위험 카페고리 넘버 | 8-36/37/38-20/21/22 | ||
안전지침서 | 36/37/39-26-17-36 | ||
유엔번호(UN No.) | 3098 | ||
WGK 독일 | 3 | ||
RTECS 번호 | PA5360000 | ||
위험 등급 | 5.1 | ||
포장분류 | III | ||
HS 번호 | 29049095 | ||
기존화학 물질 | KE-03689 |
그림문자(GHS): | ||||||||||||||||||||||||||||||||||||
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신호 어: | Danger | |||||||||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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브로모나이트로메테인 C화학적 특성, 용도, 생산
화학적 성질
Bromonitromethane is a clear yellow liquid, It is a strong oxidizing agent with properties similar to nitromethane.Bromonitromethane has been used:
in production of various protected α-bromo nitroalkane donors (including Fmoc) for use in Umpolung amide synthesis.
in preparation of (Z)-1-bromo-1-nitroalkenes via sodium iodide-catalyzed Henry reaction.
in diastereo- and enantioselective cyclopropanation of β,γ-unsaturated a-ketoesters via domino Michael-addition/intramolecular-alkylation strategy.
용도
Bromonitromethane has received considerable attention as a one-carbon synthon for the synthesis of a variety of important organic intermediates.Bromonitromethane is a key starting material for the preparation of the broad-spectrum antibiotic trovafloxacin, which contains the interesting 3-azabicyclo[ 3.1.0]hexane ring system.
it was used in the synthesis of 2-nitrobenzofuran and 2-nitro-2,3-dihydrobenzofuran-3-ols, nitrobenzothio-phenes, and nitrothiazoles, polyfunctionalized nitrocyclopropanes. It has also been utilized in the synthesis of 1-bromo-1-nitroalkan-2-ols and aryl nitromethanes. In addition, it could be used as a bromine donor.
제조 방법
Bromonitromethane is commercially available and can also be easily prepared according to the procedures reported by Fishwick et al. A typical procedure is as following: freshly distilled nitromethane was stirred at 0℃ and bromine was dropped in 5 seconds. The resulted bromonitromethane could be used without further purification.브로모나이트로메테인 준비 용품 및 원자재
원자재
준비 용품
브로모나이트로메테인 공급 업체
글로벌( 135)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
Richest Group Ltd | 18017061086 |
oled@richest-group.com | CHINA | 5601 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23555 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15394 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 8672 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 |
sales@dogechemical.com | China | 4128 | 58 |
브로모나이트로메테인 관련 검색:
메탄 나이트로메테인 다이브로모-2-나이트로에탄올 2-브로모-2-나이트로프로페인 브로모나이트로메테인 브로노폴
Bromophenol Red
Bromophenol Blue
Bromophenol blue aqueous solution
Bromothymol Blue
beta-Bromostyrene
2-Bromo-2-methylpropane
tribromonitromethane
nibroxane
5-Bromo-5-nitro-1,3-dioxane
Debropol
BROMOCHLORONITROMETHANE
2-Bromo-2-nitroethanol