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5-플루오로-1,3-다이메틸우라실

5-플루오로-1,3-다이메틸우라실 구조식 이미지

카스 번호:: 3013-92-1

한글명:: 5-플루오로-1,3-다이메틸우라실

동의어(한글):: 5-플루오로-1,3-다이메틸우라실

상품명:: 5-FLUORO-1,3-DIMETHYLURACIL

동의어(영문):: Fluorouracil-001;Fluorouracil Impurity 34;1,3-dimethyl-5-fluorouracil;5-FLUORO-1,3-DIMETHYLURACIL;5-Fluoro-1,3-dimethyluracil 99%;5-fluoro-1,3-dimethylpyrimidine-2,4-dione;5-fluoro-1,3-diMethylpyriMidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione,5-fluoro-1,3-dimethyl-;1,3-Dimethyl-5-fluorouracil, 2,4-Dihydroxy-1,3-dimethyl-5-fluoropyrimidine

CBNumber:: CB8116404

분자식:: C6H7FN2O2

포뮬러 무게:: 158.13

MOL 파일:: 3013-92-1.mol

속성

안전

용도

공급 업체 23

5-플루오로-1,3-다이메틸우라실 속성

녹는점: 132-134 °C(lit.)

끓는 점: 182.5±50.0 °C(Predicted)

밀도: 1.37±0.1 g/cm3(Predicted)

산도 계수 (pKa): -4.07±0.40(Predicted)

BRN: 880396

안전

안전지침서	22-24/25
WGK 독일	3

5-플루오로-1,3-다이메틸우라실 C화학적 특성, 용도, 생산

용도

5-Fluoro-1,3-dimethyluracil may be used as starting material in the following processes:

Regioselective synthesis of tetrahydronaphthocyclobuta[1,2-d]pyrimidinediones.
To synthesize 5-bis(ethoxycarbonyl)methyl-1,3-dimethyluracil.
To synthesize new highly conjugated propenylidene derivatives via aromatic Paterno-Buchi type cycloaddition with 1-methoxynaphthalene.

Synthesis Reference(s)

Tetrahedron, 46, p. 3093, 1990 DOI: 10.1016/S0040-4020(01)88400-3

일반 설명

Oxidation of 5-fluoro-1,3-dimethyluracil (5-FDMU) with m-chloroperbenzoic acid has been described. It is reported as antineoplastic drug. On photoirradiation, 5-fluoro-1,3-dimethyluracil yields the trans-anti cyclobutane dimer and the cis-syn cyclobutane dimer. UV irradiation of 5-FDMU and naphthalene in a protic medium affords 5-(1-naphthyl)uracil, while in aprotic media it undergoes stereoselective 1,4-cycloaddition reaction to give a barrelene derivative. The thermochemical parameters of 5-FDMU has been determined. It reacts with substituted benzenes in the presence of trifluoroacetic acid to generate 5-aryl-1,3-dimethyluracils via photosubstitution.

5-플루오로-1,3-다이메틸우라실 준비 용품 및 원자재

원자재

준비 용품

5-플루오로-1,3-다이메틸우라실 공급 업체

글로벌( 23)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3487	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Chemwill Asia Co.,Ltd.	86-21-51086038	chemwill_asia@126.com	CHINA	23931	58
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696;	info@hanhongsci.com	China	42982	64
Syntechem Co.,Ltd		info@syntechem.com	China	12990	57
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd.	0531-58897130 15508676053	drug_impurity@sdcclh.com	China	1743	58
Ningbo Zeyu Chemical Technology Co., Ltd	15066123231 15066123231	2278736577@qq.com	China	505	58

5-플루오로-1,3-다이메틸우라실 관련 검색:

1,3-디메틸우라실 5-플루오로-1,3-다이메틸우라실 5-fluoro-3-methyl-1H-pyrimidine-2,4-dione 5-Fluoropyrimidine (5-FLUORO-2,6-DIOXO-3-TETRAHYDROFURAN-2-YL-3,6-DIHYDROPYRIMIDIN-1(2H)-YL)ACETIC ACID ETHYL [5-FLUORO-3-(4-METHOXY-3-NITROBENZYL)-2,6-DIOXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL]ACETATE 1-acetyl-3,2-toluyl-5-fluorouracil FD 1 3-ALLYL-5-FLUORO-1-(4-METHOXY-3-NITROBENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE EMITEFUR