RUBRATOXINA

RUBRATOXINA 구조식 이미지
카스 번호:
22467-31-8
상품명:
RUBRATOXINA
동의어(영문):
RUBRATOXINA;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
CBNumber:
CB81405198
분자식:
C26H32O11
포뮬러 무게:
520.528
MOL 파일:
22467-31-8.mol

RUBRATOXINA 속성

녹는점
210-214℃ (decomposition)
저장 조건
Store at -20°C
용해도
Acetonitrile: soluble; DMSO: soluble
물리적 상태
분말
색상
하얀색
안전
  • 위험 및 안전 성명
유해 물질 데이터 22467-31-8(Hazardous Substances Data)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
2 0

RUBRATOXINA C화학적 특성, 용도, 생산

개요

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

용도

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

RUBRATOXINA 준비 용품 및 원자재

원자재

준비 용품


RUBRATOXINA 공급 업체

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Aladdin Scientific
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Shanghai Hongye Biotechnology Co. Ltd 400-9205774
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939
shenlinxing@macklin.cn China 29803 58
United States Biological --
sales@advtechind.com United States 6106 58

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