SECURININE
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SECURININE 속성
- 녹는점
- 140-1420C
- 알파
- D20 -1042° (c = 1 in alc)
- 끓는 점
- 357.82°C (rough estimate)
- 밀도
- 1.30±0.1 g/cm3 (20 ºC 760 Torr)
- 굴절률
- 1.5300 (estimate)
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- DMSO: ≥25mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 8.29±0.20(Predicted)
- 색상
- 노란색
- optical activity
- [α]/D -980 to -1015 (C=1, MeOH)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 23/24/25-22 | ||
안전지침서 | 36/37/39-45 | ||
WGK 독일 | 3 | ||
RTECS 번호 | VS4115000 |
SECURININE C화학적 특성, 용도, 생산
개요
A constituent of the leaves of Securinega suffructicosa Rehd., the base also occurs in Phyllanthus disco ides. It is obtained as yellow crystals and is strongly laevorotatory having [α]20D - 1106°(CHC13), [α]30D - 1106°(CHC13) and[α]20D - 1042° (c 1.0, EtOH). The alkaloid yields a crystalline methiodide, m.p. 235-6°C.화학적 성질
Yellow Solid용도
Extracted from leaves and roots of Securinega suffruticosa Rehder. The most widely studied of these alkaloids, Securinine, is a specific GABA receptor antagonist and has been found to have significant in vivo CNS activity.참고 문헌
Murav'eva, Ban'kovskii., Dokl. Akad. Nauk, SSSR, 110,998 (1956)Saito et al., Chem. & Ind., 1652 (1962)
Satoda et al., Tetrahedron Lett., 1199 (1962)
Mukherjee et al., Naturwiss., 50, 155 (1963)
Nakano et aI., Chem. & Ind., 1763 (1963)
Horii et al., ibid, 664 (1964)
Bevan et aI., ibid, 838 (1964)
Absolute configuration:
Bevan et al., Chern. Ind., 838 (1964)
Imadoetal., ibid, 1691 (1964)
Synthesis:
Horii et al., Tetrahedron, 23, 2265 (1967)
SECURININE 준비 용품 및 원자재
원자재
준비 용품
SECURININE 공급 업체
글로벌( 160)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 |
marketing1@neostarunited.com | China | 8349 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 |
sales@chemnorm.com | CHINA | 2935 | 58 |
Aktin Chemicals, Inc. | 028-85159085 |
info@aktinchem.com | CHINA | 1025 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29220 | 58 |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9427 | 58 |