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ChemicalBook >제품 카탈로그 >2'-O-MOE-A(Bz)-3'-phosphoramidite

2'-O-MOE-A(Bz)-3'-phosphoramidite

2'-O-MOE-A(Bz)-3'-phosphoramidite 구조식 이미지
카스 번호:
251647-53-7
상품명:
2'-O-MOE-A(Bz)-3'-phosphoramidite
동의어(영문):
DMT-2'-O-MOE-A(Bz)-CE;2’-MOE-dA(Bz) Amidite;N6-Bz-5'-O-DMT-2'-O-MOE-A-CE;2'-O-MOE-Bz-A Phosphoramidite;2'-MOE-N-Bz Adenosine Amidite;2'-MOE-Bz-A CE Phosphoramidite;2'-O-MOE-rA(Bz) Phosphoramidite);2'-O-MOE-A(Bz)-3'-phosphoramidite;2'-O-MOE-A(Bz)-CE Phosphoramidite;2'-O-MOE-A(Bz)-3'-phosphoramidite
CBNumber:
CB83051689
분자식:
C50H58N7O9P
포뮬러 무게:
932.01
MOL 파일:
251647-53-7.mol
MSDS 파일:
SDS

2'-O-MOE-A(Bz)-3'-phosphoramidite 속성

산도 계수 (pKa)
7.87±0.43(Predicted)
InChIKey
VPBYBQBHLYRLHG-VCCSSPGHNA-N
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P312 삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P330 입을 씻어내시오.
P501 ...에 내용물 / 용기를 폐기 하시오.

2'-O-MOE-A(Bz)-3'-phosphoramidite C화학적 특성, 용도, 생산

개요

2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

화학적 성질

The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.

2'-O-MOE-A(Bz)-3'-phosphoramidite 준비 용품 및 원자재

원자재

준비 용품

2'-O-MOE-A(Bz)-3'-phosphoramidite 공급 업체

글로벌( 102)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Zhejiang Hengkang Pharmaceutical Co., Ltd.
+86-576-83372028 +86-18868723926
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Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715
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Chemtour Biotech Co., Ltd 		+8617327281506
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Hefei Huana Biomedical Technology Co.,Ltd. 		+86-15900695956
shiqin.he@huanaok.com.cn China 96 58
SHANGHAI NOVRIBO BIOTECH 		17821030819
 June.Liu@Desano.com China 73 58

2'-O-MOE-A(Bz)-3'-phosphoramidite 관련 검색:

2'-O-Methylcytidine DMT-2μ-O-Me-rG(ib) amidite 2’-O-Methyl-rA(N-Bz)phosphoramidite DMT-2′Fluoro-dU Phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite 2'-O-Methyladenosine 2'-O-(2-Methoxyethyl)cytidine 2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-OMe-ibu-G Phosphoramidite 2'-O-(2-Methoxyethyl)guanosine
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