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2'-O-MOE-A(Bz)-3'-phosphoramidite

2'-O-MOE-A(Bz)-3'-phosphoramidite structure

CAS No.: 251647-53-7

Chemical Name:: 2'-O-MOE-A(Bz)-3'-phosphoramidite

Synonyms: DMT-2'-O-MOE-A(Bz)-CE;2’-MOE-dA(Bz) Amidite;N6-Bz-5'-O-DMT-2'-O-MOE-A-CE;2'-O-MOE-Bz-A Phosphoramidite;2'-MOE-N-Bz Adenosine Amidite;2'-MOE-Bz-A CE Phosphoramidite;2'-O-MOE-rA(Bz) Phosphoramidite);2'-O-MOE-A(Bz)-3'-phosphoramidite;2'-O-MOE-A(Bz)-CE Phosphoramidite;2'-O-MOE-A(Bz)-3'-phosphoramidite

CBNumber:: CB83051689

Molecular Formula:: C50H58N7O9P

Molecular Weight:: 932.01

MDL Number:: MFCD29472587

MOL File:: 251647-53-7.mol

Last updated:2024-01-23 16:00:19

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2'-O-MOE-A(Bz)-3'-phosphoramidite Properties

pka	7.87±0.43(Predicted)
InChIKey	VPBYBQBHLYRLHG-VCCSSPGHNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501

2'-O-MOE-A(Bz)-3'-phosphoramidite price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B207938	N6-Benzoyl-5''-O-DMT-2''-O-(2-methoxyethyl)adenosine3''-CEPhosphoramidite	251647-53-7	50mg	$65	2021-12-16	Buy
Biosynth Carbosynth	PB59569	N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite	251647-53-7	250mg	$90	2021-12-16	Buy
Biosynth Carbosynth	PB59569	N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite	251647-53-7	500mg	$150	2021-12-16	Buy
Biosynth Carbosynth	PB59569	N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite	251647-53-7	1g	$275	2021-12-16	Buy
Biosynth Carbosynth	PB59569	N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite	251647-53-7	2g	$500	2021-12-16	Buy

Product number	Packaging	Price	Buy
B207938	50mg	$65	Buy
PB59569	250mg	$90	Buy
PB59569	500mg	$150	Buy
PB59569	1g	$275	Buy
PB59569	2g	$500	Buy

2'-O-MOE-A(Bz)-3'-phosphoramidite Chemical Properties,Uses,Production

Description

2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

Chemical Properties

The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.

Uses

N6-Benzoyl-5''-O-DMT-2''-O-(2-methoxyethyl)adenosine 3''-CE phosphoramidite (CAS# 251647-53-7) is used diagnostically in the screening of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) oligonucleotidic modulators.

2'-O-MOE-A(Bz)-3'-phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

2'-O-MOE-A(Bz)-3'-phosphoramidite Suppliers

Global( 102)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Hengkang Pharmaceutical Co., Ltd.	+86-576-83372028 +86-18868723926	bd1@hengkangpharm.cn	China	119	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15932	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +undefined17756524438	sales1@nuowei-chem.com	China	1642	58
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
Hefei Huana Biomedical Technology Co.,Ltd.	+86-15900695956	shiqin.he@huanaok.com.cn	China	96	58
SHANGHAI NOVRIBO BIOTECH	17821030819	June.Liu@Desano.com	China	73	58

Supplier	Advantage
Zhejiang Hengkang Pharmaceutical Co., Ltd.	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
Career Henan Chemica Co	58
NewCan Biotech Limited	58
Wuhu Nuowei chemistry Co., Ltd.	58
Chemtour Biotech Co., Ltd	58
Hefei Huana Biomedical Technology Co.,Ltd.	58
SHANGHAI NOVRIBO BIOTECH	58

View Lastest Price from 2'-O-MOE-A(Bz)-3'-phosphoramidite manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-04-04	DMT-2′O-MOE-rA(bz) Phosphoramidite 251647-53-7	US $0.00-0.00 / kg	1kg	98%	500kg per month	Zhejiang Hengkang Pharmaceutical Co., Ltd.
2023-03-21	2'-MOE-Bz-A CE Phosphoramidite 251647-53-7	US $100.00 / kg	0.009999999776482582kg	99%	5tons	SHANGHAI NOVRIBO BIOTECH
2023-03-14	N6-Bz-5'-O-DMT-2'-O-MOE-A-CE 251647-53-7	US $0.00 / mg	100mg	≥98%	20tons	Hefei Huana Biomedical Technology Co.,Ltd.

DMT-2′O-MOE-rA(bz) Phosphoramidite
251647-53-7
US $0.00-0.00 / kg
98%
Zhejiang Hengkang Pharmaceutical Co., Ltd.

2'-MOE-Bz-A CE Phosphoramidite
251647-53-7
US $100.00 / kg
99%
SHANGHAI NOVRIBO BIOTECH

N6-Bz-5'-O-DMT-2'-O-MOE-A-CE
251647-53-7
US $0.00 / mg
≥98%
Hefei Huana Biomedical Technology Co.,Ltd.

251647-53-7(2'-O-MOE-A(Bz)-3'-phosphoramidite)Related Search:

2'-O-Methylcytidine DMT-2μ-O-Me-rG(ib) amidite 2’-O-Methyl-rA(N-Bz)phosphoramidite DMT-2′Fluoro-dU Phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine

N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite 2'-O-Methyladenosine 2'-O-(2-Methoxyethyl)cytidine

2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-OMe-ibu-G Phosphoramidite

2'-O-(2-Methoxyethyl)guanosine

1of4

2'-O-MOE-A(Bz)-3'-phosphoramidite N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI) 2'-O-MOE-Bz-A Phosphoramidite N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite 2'-O-MOE-A(Bz)-CE Phosphoramidite 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite 2'-O-MOE-rA(Bz) Phosphoramidite) 5'-O-DMT-N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N6-benzoyl-adenosine -3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite 5'-DMTr-2'-MOE-N6-Bz-3'-CEP-Adenosine 5'-DMTr-2'-MOE-N6Bz-3'-O-CEP-ADENOSINE DMT-2′O-MOE-rA(bz) Phosphoramidite 2’-O-MOE-A(Bz)-3’-phospho ramidite, N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite N6-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)-adenosine-3’-CED-phosphoramidite N6-Bz-5'-O-DMT-2'-O-MOE-A-CE 5'-O-DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite 2'-MOE-Bz-A CE Phosphoramidite 5'-O-DMT-2'-O-MOE-N6-Benzoyl- Adenosine -3’-Cyanoethyl Phosphoramidite 2'-MOE-N-Bz Adenosine Amidite DMT-2'-O-MOE-A(Bz)-CE DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite 2’-MOE-dA(Bz) Amidite N6-Benzoyl-2-o-methyladenosine 3-ce phosphoramidite N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-O-(2-methoxyethyl)adenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-ODMT-2'-OMOE-N-Bz Adenosine-3'-OCEPA 2'-O-MOE-A(Bz)-3'-phosphoramidite DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite 251647-53-7 C50H58N7O9P Amidite