PEPLOMYCIN SULFATE
|
|
PEPLOMYCIN SULFATE 속성
- 녹는점
- 196-198°C
- 알파
- 25436 -2.0° (c = 1 in water)
- 용해도
- DMSO, DMF, 메탄올, 물에 용해됨
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 2.9, 4.8, 7.4, 9.0(at 25℃)
- 색상
- 담황색 무정형
안전
독성 | LD50 in male rats, mice (mg/kg): 234, 88 s.c.; 208, 85 i.p.; 245, 51 i.v. (Ito) | ||
---|---|---|---|
기존화학 물질 | KE-28361 |
PEPLOMYCIN SULFATE C화학적 특성, 용도, 생산
개요
Peplomycin was derived biosynthetically from Streptomyces verticillus, the bleomycinproducing organism, in the course of efforts to obtain bleomycin derivatives with high activity and low toxicity. This antibiotic was found by Nippon Kayaku Co. and the Institute of Microbial Chemistry, Japan, in 1974. Its anticancer effects appear earlier than those of bleomycin; consequently, the period of therapy is shortened. Peplomycin is also active against metastatic cancer of the lymph nodes and shows less pneumotoxicity than bleomycin.화학적 성질
Pale Yellow Amorphous PowderSafety Profile
Poison by intraperitoneal, subcutaneous, and intravenous routes. Questionable carcinogen with experimental carcinogenic data. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx.PEPLOMYCIN SULFATE 준비 용품 및 원자재
원자재
준비 용품
PEPLOMYCIN SULFATE 공급 업체
글로벌( 16)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55717 | 58 |