ALDOSTERONE
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ALDOSTERONE 속성
- 녹는점
- 170-172°C
- 알파
- D23 +152.2° (anhydr; c = 2 in acetone); D25 +161° (c = 0.1 in chloroform)
- 끓는 점
- 412.46°C (rough estimate)
- 밀도
- 1.28
- 굴절률
- 1.6120 (estimate)
- 인화점
- 2℃
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 아세톤(약간 용해됨), 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 12.98±0.10(Predicted)
- 물리적 상태
- 결정성 분말
- 색상
- 하얀색
- optical activity
- +14523 (c 0.99, acetone)
- 수용성
- 51.18mg/L(37℃)
- Merck
- 13,224
- BRN
- 3224996
- CAS 데이터베이스
- 52-39-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,Xn,F | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-36-20/21/22-11 | ||
안전지침서 | 22-24/25-36-26-36/37-16 | ||
유엔번호(UN No.) | UN 1648 3 / PGII | ||
WGK 독일 | 3 | ||
RTECS 번호 | TU4523000 | ||
F 고인화성물질 | 22-24-25 | ||
HS 번호 | 29372900 |
ALDOSTERONE C화학적 특성, 용도, 생산
개요
Aldosterone is a mineralocorticosteroid that takes part in the regulation of electrolytic balance in the organism. Aldosterone lowers excretion of sodium ions from the body, thus increasing their reabsorption and increasing secretion of potassium ions in renal tubules. Being a competitive antagonist of aldosterone, spironlactone blocks aldosterone receptors, thus increasing excretion of sodium, chloride, and corresponding equivalents of water with urine, thus retaining the amount of potassium ions in the organism. Spironolactone is used both individually as well as in combination with thiazides, since it lowers kaliuresis caused by thiazide diuretics.화학적 성질
White Solid용도
Labelled Aldosterone. Aldosterone is an adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid pr oduced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal.정의
ChEBI: A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, i creased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.건강위험
Aldosterone(Aldocortin; electrocortin; mineralocorticoid; 18-oxocorticosterone): (1)Maintenance of normal electrolyte blood balances;(2)Prolongs survival of adrenalectomized animals;(3)Accelerates gluconeogenesis;(4)Regulates kidney function.Purification Methods
Crystallise aldosterone from aqueous acetone. It exists in solution as an equilibrium mixture of free aldehyde and its cyclic hemiacetal, favouring the hemiacetal. The 21-acetate crystallises from Me2CO/Et2O or CH2Cl2/EtOAc and has m 198-199o, [] D +121.7o (c 0.7, CHCl3). [Barton et al. J Chem Soc Perkin Trans 1 2243 1975, Beilstein 8 IV 3491.]ALDOSTERONE 준비 용품 및 원자재
원자재
Sodium triacetoxyborohydride
D-ALDOSTERONE 21-ACETATE
Pregn-4-en-18-oic acid, 11,21-dihydroxy-3,20-dioxo-, γ-lactone, (11β)- (9CI)
Pregn-4-en-18-oic acid, 21-(acetyloxy)-11-hydroxy-3,20-dioxo-, γ-lactone, (11β)- (9CI)
Pregn-5-en-18-oic acid, 3,3:20,20-bis[1,2-ethanediylbis(oxy)]-11,21-dihydroxy-, γ-lactone, (11β)- (9CI)
준비 용품
ALDOSTERONE 공급 업체
글로벌( 180)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15394 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9640 | 58 |
ALDOSTERONE 관련 검색:
D-ALDOSTERONE 21-ACETATE,ALDOSTERONE 21-ACETATE
D-ALDOSTERONE 18,21-DIACETATE
ALDOSTERONE 3-CMO : BSA
ALDOSTERONE SECRETION INHIBITING FACTOR (1-35) (BOVINE)
Aldosterone ELISA
ALDOSTERONE, D-[1,2-3H(N)]-,[1,2-3H]ALDOSTERONE
ANTI-ALDOSTERONE-3
ALDOSTERONE LABELING POSITION:3
ALDOSTERONE 3-CMO : HISTAMINE
ALDOSTERONE SODIUM SULPHATE
[1,2,6,7-3H]ALDOSTERONE,ALDOSTERONE, [1,2,6,7-3H]-,ALDOSTERONE, D [1,2,6,7-3H(N)]
ALDOSTERONE 18,21-DIACETATE
ALDOSTERONE GAMMA LACTONE
Aldosterone, bis(O-trimethylsilyl-)
D-ALDOSTERONE 21-HEMISUCCINATE*CRYSTALLINE
ALDOSTERONE-3-BSA,RABBITANTI-:RIA
ALDOSTERONE ANTI- KV FOR 3H
MAb to Aldosterone Purified (1)