PAGOCLONE

PAGOCLONE 구조식 이미지
카스 번호:
133737-32-3
상품명:
PAGOCLONE
동의어(영문):
Ip 456;CI-1043;RP 59037;AGOCLONE;Rp 62955;(+)-Pagoclone;(+)-RP-59037; IP-456; RP-62955; CI-1043;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor
CBNumber:
CB8839954
분자식:
C23H22ClN3O2
포뮬러 무게:
407.89
MOL 파일:
133737-32-3.mol

PAGOCLONE 속성

끓는 점
582.1±50.0 °C(Predicted)
밀도
1.273±0.06 g/cm3(Predicted)
산도 계수 (pKa)
1.62±0.30(Predicted)
InChI
InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKey
HIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2

안전

PAGOCLONE C화학적 특성, 용도, 생산

개요

Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.

용도

Anti-anxiety agent.

상표명

Bextra (Interneuron).

PAGOCLONE 준비 용품 및 원자재

원자재

준비 용품


PAGOCLONE 공급 업체

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