3,5-difluorobenzophenone
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3,5-difluorobenzophenone 속성
- 녹는점
- 57-59°C
- 끓는 점
- 117°C 5mm
- 밀도
- 1.239±0.06 g/cm3(Predicted)
- 인화점
- 116-118°C/5mm
- 저장 조건
- 2-8°C
- 물리적 상태
- 결정질 고체
- 색상
- 노란색
- BRN
- 7919206
- CAS 데이터베이스
- 179113-89-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
3,5-difluorobenzophenone C화학적 특성, 용도, 생산
제조 방법
Synthesis of 3,5-Difluorobenzophenone: Prior to acylations, 3,5-difluorobenzoic acid was reacted with freshly distilled thionyl chloride and catalytic amounts of DMF(2 drops). After two hours at 55 °C, the excess thionyl chloride was distilled between 75 and 77 °C. The acid halide was then fractionally distilled at 174 °C, and recovery was generally around 75%. To a 50 mL round bottom flask, equipped with a gas inlet, addition funnel, condenser, and drying tube, were added 3.01 g (22.6 mmol) of AlCl3. A mixture of 3.62 g (20.5 mmol) 3,5-difluorobenzoyl chloride and 8.01 g (102.5 mmol) benzene was added dropwise to the AlCl3. The reaction mixture was stirred for 4 hours, before heating to 75 °C. After 16 hours the reaction mixture was quenched by pouring into acidic ice water, followed by addition of 300 mL of chloroform, and transferring to a separatory funnel. The layers were separated and the organic layer was washed with 5 wt. % bicarbonate, distilled water, and then dried with MgSO4 and the solvents were removed, via rotary evaporation, leaving an off-white solid. The crude material was recrystallized from aqueous ethanol to afford (3.00 g, 67 %) of a crystalline white solid with a m.p. 58-59 °C (lit.21 m.p. 57-58 °C); 1H NMR (300 MHz, CDCl3, δ) 7.04 (tt, 1H, J = 8.4, 2.4 Hz), 7.31 (m, 2H), 7.51 (m, 2H), 7.63 (tt, 1H, J = 7.5, 1.2 Hz), 7.78 (m, 2H)3,5-difluorobenzophenone 준비 용품 및 원자재
원자재
준비 용품
3,5-difluorobenzophenone 공급 업체
글로벌( 68)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 |
sophieliu@speranzachem.com | China | 801 | 55 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 |
contact@fuxinpharm.com | China | 10297 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
sales@win-winchemical.com | China | 14350 | 58 |
Sense Chemicals (Shanghai) Co., Ltd. | +86-21-52751036; +8613818977689 |
david.dai@sensechemicals.com | China | 225 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 |
sales@tnjchem.com | China | 25363 | 58 |
Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 |
CB@aromsyn.com | China | 19185 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +8619930503259 |
cherry@crovellbio.com | China | 18420 | 58 |
Aceschem Inc. | +1-817863-6948 +1-(817)863-6948 |
sales@aceschem.com | United States | 19639 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
3,5-difluorobenzophenone 관련 검색:
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3,5-difluorobenzophenone
2,3,4,5,6-PENTAFLUOROBENZOPHENONE
3,4,5-TRIFLUOROBENZOPHENONE
DECAFLUOROBENZOPHENONE
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3,3'-Difluorobenzophenone
2,6-Difluorobenzophenone 98%,2,6-Difluorobenzophenone, 97+%,2,6-Difluorobenzophenone,98%,2,6-DIFLUOROBENZOPHENONE
p,p’-difluorobenzophenon
2,5-DIFLUOROBENZOPHENONE,2,5-Difluorobenzophenone, 97+%,2,5-Difluorobenzophenone 97%
4,4’-Difluorobenzophenone,hydroquinonepolyme
METHOXYPHENONE
4-CHLORO-3',5'-DIFLUOROBENZOPHENONE
2-CHLORO-3',5'-DIFLUOROBENZOPHENONE
3,5-DIFLUORO-4'-PIPERIDINOMETHYL BENZOPHENONE