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3,5-difluorobenzophenone

3,5-difluorobenzophenone 구조식 이미지

카스 번호:: 179113-89-4

상품명:: 3,5-difluorobenzophenone

동의어(영문):: 3,5-DIFLUOROBENZOPHENONE;3,5-Difluorobenzophenone97%;3,5-Difluorobenzophenone 97%;3,5-DIFLUOROBENZOPHENONE, 98+%;(3,5-Difluorophenyl)(phenyl)methanone;Methanone, (3,5-difluorophenyl)phenyl-

CBNumber:: CB9122835

분자식:: C13H8F2O

포뮬러 무게:: 218.2

MOL 파일:: 179113-89-4.mol

속성

안전

용도

공급 업체 70

3,5-difluorobenzophenone 속성

녹는점: 57-59°C

끓는 점: 117°C 5mm

밀도: 1.239±0.06 g/cm3(Predicted)

인화점: 116-118°C/5mm

저장 조건: 2-8°C

물리적 상태: 결정질 고체

색상: 노란색

BRN: 7919206

CAS 데이터베이스: 179113-89-4(CAS DataBase Reference)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xi
위험 카페고리 넘버	36/37/38
안전지침서	26-36
위험 등급	IRRITANT
HS 번호	2914390090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P405	밀봉하여 저장하시오.

NFPA 704

	1
2		0

3,5-difluorobenzophenone C화학적 특성, 용도, 생산

제조 방법

Synthesis of 3,5-Difluorobenzophenone: Prior to acylations, 3,5-difluorobenzoic acid was reacted with freshly distilled thionyl chloride and catalytic amounts of DMF(2 drops). After two hours at 55 °C, the excess thionyl chloride was distilled between 75 and 77 °C. The acid halide was then fractionally distilled at 174 °C, and recovery was generally around 75%. To a 50 mL round bottom flask, equipped with a gas inlet, addition funnel, condenser, and drying tube, were added 3.01 g (22.6 mmol) of AlCl3. A mixture of 3.62 g (20.5 mmol) 3,5-difluorobenzoyl chloride and 8.01 g (102.5 mmol) benzene was added dropwise to the AlCl3. The reaction mixture was stirred for 4 hours, before heating to 75 °C. After 16 hours the reaction mixture was quenched by pouring into acidic ice water, followed by addition of 300 mL of chloroform, and transferring to a separatory funnel. The layers were separated and the organic layer was washed with 5 wt. % bicarbonate, distilled water, and then dried with MgSO4 and the solvents were removed, via rotary evaporation, leaving an off-white solid. The crude material was recrystallized from aqueous ethanol to afford (3.00 g, 67 %) of a crystalline white solid with a m.p. 58-59 °C (lit.21 m.p. 57-58 °C); 1H NMR (300 MHz, CDCl3, δ) 7.04 (tt, 1H, J = 8.4, 2.4 Hz), 7.31 (m, 2H), 7.51 (m, 2H), 7.63 (tt, 1H, J = 7.5, 1.2 Hz), 7.78 (m, 2H)

3,5-difluorobenzophenone 준비 용품 및 원자재

원자재

Benzenecarbothioic acid, S-phenyl ester 3,5-Difluorophenylboronic acid Benzoic acid pentafluorophenyl ester, BzOPfp

준비 용품

3,5-difluorobenzophenone 공급 업체

글로벌( 70)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	723	55
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
WinWin Chemical CO., Limited	+86-0577-64498589 +8615325081899	sales@win-winchemical.com	China	13854	58
Sense Chemicals (Shanghai) Co., Ltd.	+86-21-52751036; +8613818977689	david.dai@sensechemicals.com	China	224	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19185	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18455	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19639	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58

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