tert-부틸2-옥소-7-아자스피로[3.5]노난-7-카르복실레이트
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tert-부틸2-옥소-7-아자스피로[3.5]노난-7-카르복실레이트 속성
- 녹는점
- 55-56℃
- 끓는 점
- 349℃
- 밀도
- 1.12
- 인화점
- 165℃
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- -0.80±0.20(Predicted)
- 색상
- 맑은 노란색
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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tert-부틸2-옥소-7-아자스피로[3.5]노난-7-카르복실레이트 C화학적 특성, 용도, 생산
화학적 성질
White powderSynthesis
To a flame-dried RB flask with tert-butyl 4-methylenepiperidine-1- carboxylate (2.96 g, 15 mmol, 1.0 equiv) and Zn/Cu couple (6.54 g, 172.5 mmol, 11.5 equiv) under vacuum, t-BuOMe (60 mL) was charged and refilled the flask with N2 balloon. To the mixture thus obtained stirred at 15 °C, a solution of 2,2,2- trichloroacetyl chloride in DME (20 mL) was added dropwise. The mixture was stirred at room temperature overnight after addition. To the reaction mixture stirred in an external ice- bath, a saturated solution of NH4CI (60 mL) was added slowly and carefully (especially the first few drops). After addition, the mixture was stirred at room temperature for 4 h and filtered to remove the solid. The phases were separated. The aqueous phase was extracted with EtOAc. The combined organic phase was washed with brine, dried over anhydrous Na2S04, and concentrated to give the residue, which was purified by CombiFlash (40 g silica gel column, EtOAc/Hexane: 0-40percent) to afford 619 mg (15%) of tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate.tert-부틸2-옥소-7-아자스피로[3.5]노난-7-카르복실레이트 준비 용품 및 원자재
원자재
준비 용품
tert-부틸2-옥소-7-아자스피로[3.5]노난-7-카르복실레이트 공급 업체
글로벌( 161)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10991 | 58 |
Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9308 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7621 | 58 |
Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 19536 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29822 | 58 |
tert-부틸2-옥소-7-아자스피로[3.5]노난-7-카르복실레이트 관련 검색:
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate hydrochloride
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
tert-butyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate
5-Amino-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester
tert-butyl (S)-(1-(3-aminophenyl)ethyl)carbamate
tert-butyl-trans-3,4-dihydroxypyrrolidine-1-carboxylate
tert-butyl 5-methoxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
tert-butyl 4-(azetidin-3-yl)piperidine-1-carboxylate
(3R,4S)-tert-butyl 3,4-dihydroxypyrrolidine-1-carboxylate
N-BOC-3A,4,7,7A-TETRAHYDROISOINDOLE
tert-butyl 6-oxooctahydro-2H-cyclopenta[c]pyridine-2-carboxylate
tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate
tert-butyl 3-bromo-2,5-dihydro-1H-pyrrole-1-carboxylate
tert-Butyl 4-(pyrrolidin-3-yl)piperidine-1-carboxylate
Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
tert-butyl 6-hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylate