Aldehyde Reactive Probe (trifluoroacetate salt)

Aldehyde Reactive Probe (trifluoroacetate salt) 구조식 이미지
카스 번호:
627090-10-2
상품명:
Aldehyde Reactive Probe (trifluoroacetate salt)
동의어(영문):
Aldehyde Reactive Probe;YJYRTJQOEOYKFD-AEXHUXLESA-N;Aldehyde Reactive Probe (trifluoroacetate salt);ARP [N-(AMinooxyacetyl)-N'-(D-biotinoyl) hydrazine, trifluoroacetic acid salt]
CBNumber:
CB92590207
분자식:
C14H22F3N5O6S
포뮬러 무게:
445.41
MOL 파일:
627090-10-2.mol

Aldehyde Reactive Probe (trifluoroacetate salt) 속성

저장 조건
Store at -20°C
용해도
DMF: 20 mg/ml; DMSO: 15 mg/ml; PBS (pH 7.2): 3 mg/ml
물리적 상태
결정성 고체

안전

Aldehyde Reactive Probe (trifluoroacetate salt) C화학적 특성, 용도, 생산

개요

DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA. ARP reacts with aldehyde groups formed when reactive oxygen species depurinate DNA, resulting in covalent linkage of biotin to these AP sites. The biotin-tagged DNA can then be detected using common avidin-conjugated reporters such as avidin-HRP. The ARP method is highly sensitive, enabling detection of 2.4 AP sites per 1x107 nucleotides of DNA.

Aldehyde Reactive Probe (trifluoroacetate salt) 준비 용품 및 원자재

원자재

준비 용품


Aldehyde Reactive Probe (trifluoroacetate salt) 공급 업체

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