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tBuXPhos-Pd-G3 C화학적 특성, 용도, 생산
용도
tBuXPhos Pd G3 may be used to synthesize 4-cyano-7-azaindole from 4-chloro-7-azaindole by cyanation reaction. It may also be used for the α-arylation reaction of acetate esters at room temperature.
화학 반응
Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media.
일반 설명
tBuXPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. tBuXPhos Pd G3 is an excellent reagent for Buchwald-Hartwig cross-coupling reaction. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
저장
tBuXPhos Pd G3 should be stored in an airtight, dry and low temperature.
