Florbenazine
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Florbenazine 속성
- 끓는 점
- 496.0±45.0 °C(Predicted)
- 밀도
- 1.14±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 14.75±0.40(Predicted)
- InChI
- InChI=1S/C21H32FNO3/c1-14(2)9-16-13-23-7-5-15-10-21(26-8-4-6-22)20(25-3)11-17(15)18(23)12-19(16)24/h10-11,14,16,18-19,24H,4-9,12-13H2,1-3H3/t16-,18-,19-/m1/s1
- InChIKey
- GNKGXQHHUUEYQV-BHIYHBOVSA-N
- SMILES
- C12=CC(OC)=C(OCCCF)C=C1CCN1[C@]2([H])C[C@@H](O)[C@H](CC(C)C)C1
안전
Florbenazine C화학적 특성, 용도, 생산
개요
Florbenazine (AV-133) is a fluorinated VMAT-2 ligand for PET. It is designed to measure dopaminergic degeneration by in vivo assessment of striat VMAT2 density in patients with Parkinson’s disease (PD). Besides differentiating PD from essential tremor and drug-induced parkinsonism, PET imaging of VMAT2 may help in differentiating Dementia with Lewy Bodies (DLB) from Alzheimer’s disease. AV-45 (florbetapir, AmyvidTM) is the first PET ligand to receive US FDA approval to assess neuritic plaque amyloid[1-2].Florbenazine 준비 용품 및 원자재
원자재
준비 용품
Florbenazine 공급 업체
글로벌( 5)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 |
Sales@ATKchemical.com | China | 9729 | 58 |
| Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. | 027-65388397 18164111589 |
3321478047@qq.com | China | 2002 | 55 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131885 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 19370895928 |
qqyang@aikonchem.com | China | 9995 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32997 | 60 |