Taurohyodeoxycholic acid sodium salt hydrate

Taurohyodeoxycholic acid sodium salt hydrate 구조식 이미지
카스 번호:
38411-85-7
상품명:
Taurohyodeoxycholic acid sodium salt hydrate
동의어(영문):
Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;5β-CHOLANIC ACID-3α, 6α-DIOL N-(2-SULPHOETHYL)-AMIDE;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate
CBNumber:
CB9547458
분자식:
C26H46NNaO6S
포뮬러 무게:
523.7
MOL 파일:
38411-85-7.mol
MSDS 파일:
SDS

Taurohyodeoxycholic acid sodium salt hydrate 속성

저장 조건
Store at -20°C
용해도
DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
물리적 상태
결정성 고체

안전

WGK 독일 3

Taurohyodeoxycholic acid sodium salt hydrate C화학적 특성, 용도, 생산

개요

Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.

용도

Sodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.

일반 설명

Sodium taurohyodeoxycholate hydrate is a taurine-amidated bile salt, which can be used as an anionic detergent.

Taurohyodeoxycholic acid sodium salt hydrate 준비 용품 및 원자재

원자재

준비 용품


Taurohyodeoxycholic acid sodium salt hydrate 공급 업체

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