3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppliers
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
- CAS:
- 781652-57-1
- MF:
- C23H16N4O
- MW:
- 364.4
Suppliers by country/region
Properties
- Melting point:
- 210-212°C
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥5mg/mL at warmed to 60°C
- form
- powder
- color
- white to beige
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22
- WGK Germany
- 3
Use
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
85 supplier list of "3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide"
- Product Name:mGluR5 Ligand, CDPPB
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 8-Aminonaphthalene-1,3,5-trisulfonic acid disodium salt ,CAS 77890-99-4,D-CAMPHOR CAS 464-49-3,dimethylaminopropylstearamide CAS 7651-02-7,Dimethyl sulfide, CAS 75-18-3,Creatinine, CAS 60-27-5
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1mg$109.00
- Product Name:mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem
- Products Intro:Brand: Sigma-Aldrich | Product Number: 445865 | Purity: A pyrazole amide compound that crosses the blood-brain barrier and acts as a potent, selective, reversible, positive allosteric modulator for metabotropic glutamate receptor subtype 5 (mGluR5).
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof
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