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Dimethyl sulfate

CAS:
77-78-1
MF:
C2H6O4S
MW:
126.13

Properties

Melting point:
-32 °C
Boiling point:
188 °C(lit.)
Density 
1.333 g/mL at 25 °C(lit.)
vapor density 
4.3 (vs air)
vapor pressure 
0.7 mm Hg ( 25 °C)
refractive index 
n20/D 1.386(lit.)
Flash point:
182 °F
storage temp. 
2-8°C
solubility 
ethanol: 0.26 g/mL, clear, colorless
form 
Liquid
color 
Clear colorless
Odor
Almost odorless
Water Solubility 
2.8 g/100 mL (18 ºC)
Merck 
13,3282
BRN 
635994
Exposure limits
TLV/PEL-TWA skin 0.1 ppm (0.52 mg/m3 ) (ACGIH, OSHA, NIOSH) IDLH 10 ppm (NIOSH).
Stability:
Stable; combustible. Incompatible with strong oxidizing agents, strong bases including ammonia. Moisture-sensitive.

Safety Information

Symbol(GHS) 

GHS05,GHS06,GHS08
Signal word 
Danger
Hazard statements 
H301-H314-H317-H330-H341-H350
Precautionary statements 
P201-P260-P280-P301+P310+P330-P303+P361+P353-P304+P340+P310-P305+P351+P338-P308+P313-P403+P233
Hazard Codes 
T+
Risk Statements 
45-25-26-34-43-68
Safety Statements 
53-45-61
RIDADR 
UN 1595 6.1/PG 1
WGK Germany 
2
RTECS 
WS8225000
21
Autoignition Temperature
495 °C
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
29209090
Toxicity
LD50 orally in rats: 440 mg/kg (Smyth)

Use

Dimethyl sulfate is extremely hazardous because of its lack of warning properties and delayed toxic effects. The vapor of this compound is extremely irritating to the skin, eyes, and respiratory tract, and contact with the liquid can cause very severe burns to the eyes and skin. Ingestion of dimethyl sulfate causes burns to the mouth, throat, and gastrointestinal tract. The effects of overexposure to dimethyl sulfate vapor may be delayed. After a latent period of 10 hours or more, headache and severe pain to the eyes upon exposure to light may occur, followed by cough, tightness of the chest, shortness of breath, difficulty in swallowing and speaking, vomiting, diarrhea, and painful urination. Fatal pulmonary edema may develop. Systemic effects of dimethyl sulfate include damage to the liver and kidneys. Dimethyl sulfate is listed by IARC in Group 2A ("probable human carcinogen") and is classified as a "select carcinogen" under the criteria of the OSHA Laboratory Standard. Data indicate that dimethyl sulfate does not specifically harm unborn animals; dimethyl sulfate is not a developmental toxin. It is a strong alkylating agent and does produce genetic damage in animals and in bacterial and mammalian cell cultures.

188 supplier list of "Dimethyl sulfate"

  • Product Name:Dimethyl sulfate
  • Products Intro:Purity: 99 | Package: 200KG;150USD
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    $10.00/ 1PCS

  • Product Name:Dimethyl sulfate
  • Products Intro:Purity: 99% | Package: 1PCS;10USD
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  • Product Name:Glimepiride Impurity 32
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  • Product Name:DIMETHYL SULFATE
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  • Country/Region: CHINA

Dimethyl sulfate Related Search:

cis-Glimepiride[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]-carbamic acid ethyl esterortho-GliMepiride IMpuritytrans-4-Methycyclohexyl isocyanate4-(2-Aminoethyl)benzenesulfonamideGlimepiride EP Impurity JMeta-GliMepiride IMpuritymethyl hydrogen sulphate trans-4-Methylcyclohexyl amine4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamideGLIMEPIRIDE RELATED COMPOUND C (20 MG) (GLIMEPIRIDE URETHANE)3-Ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-1H-pyrrole-1-carboxamidePhenethyl isocyanateGlimepiride4-Methylcyclohexyl amineDiethyl sulfatealpha-Cyclopentylmandelic acid2-Bromo-5-Fluorotoluene
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