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ChemicalBook >> CAS DataBase List >>Icotinib

Icotinib suppliers

Icotinib

CAS:
610798-31-7
MF:
C22H21N3O4
MW:
391.42

Properties

Boiling point:
581℃
Density 
1.31
Flash point:
305℃
storage temp. 
Store at -20°C
solubility 
insoluble in H2O; ≥129.6 mg/mL in DMSO; ≥14.13 mg/mL in EtOH with ultrasonic
form 
Powder
pka
5.32±0.20(Predicted)

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P264-P270-P301+P312-P330-P501
HS Code 
29339900

Use

Icotinib (Conmana?, BetaPharma), an EGFR inhibitor, was approved by the China State FDA in 2011 for the treatment of NSCLC. Icotinib resembles erlotinib in possessing the N-(3-ethylnylphenyl) quinazolin-4-amine core scaffold of erlotinib that binds to the EGFR ATP pocket. An adjacent hydrophobic group was also retained while the solvent exposed two 2-methoxyethyoxysubstituents at the 6- and 7-positions of the quinazoline core were cyclized to afford the tetraoxacyclododecene moiety of icotinib. Efficacy and safety of icotinib as first-line therapy in patients has been evaluated for advanced NSCLC in recent clinical studies.

94 supplier list of "Icotinib"

  • Product Name:N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine
  • Products Intro:Purity: 95% Min. | Package: 1G;1KG;100KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0

$1.00/ 1KG

  • Product Name:Icotinib
  • Products Intro:Purity: 95% | Package: 1KG;1USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:Icotinib
  • Products Intro:Purity: >98% | Package: 300mg | CustNote: BOC Sciences also provides custom synthesis services for Icotinib.
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:Icotinib
  • Products Intro:Purity: 0.98 | Package: 1kg,2kg,5kg,10kg,25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
  • Product Name:Icotinib
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Icotinib
  • Products Intro:Purity: 0.99 | Package: 5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials
  • Product Name:Icotinib
  • Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: Icotinib
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: sarms
  • Product Name:Icotinib
  • Products Intro:Purity: 99 | Package: 5KG;1KG,25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Palmitoylethanolamide,GHK-Cu,Copper tripeptide-1,Nicotinamide Riboside Chloride,NMN,Ergothioneine
  • Product Name:Icotinib,apotentEGFRinhibitor
  • Products Intro:Purity: 0.98 | Package: 100mg;1g;500g | CustNote: Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical intermediates,raw materials,small molecule inhibitors,food additives,Biochemical reagents
  • Product Name:Icotinib
  • Products Intro:Purity: >=99% | Package: $117.9/5mg;$189.9/10mg;$662.9/50mg;Bulk package | CustNote: 99%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
You can find Icotinib suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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