Terfenadine manufacturers and suppliers

Terfenadine suppliers

Properties

Melting point:: 145-152 °C

Boiling point:: 572.76°C (rough estimate)

Density: 1.0488 (rough estimate)

refractive index: 1.6310 (estimate)

storage temp.: 2-8°C

solubility: chloroform: soluble250 mg plus 5 ml of solvent, clear to very slightly hazy, colorless to faintly yellow

pka: pKa 9.21(H2O t = 25 I = 0.025) (Uncertain)

color: White to Off-White

Water Solubility: 0.001 g/100 mL (30 ºC)

Safety Information

Symbol(GHS): GHS07,GHS08,GHS09

Signal word: Danger

Hazard statements: H413

Precautionary statements: P273-P501

Safety Statements: 24/25

WGK Germany: 2

RTECS: TM4969000

HS Code: 29333999

Toxicity: LD50 orally in mice: >2000 mg/kg (Carr, Meyer)

Use

The first clinically interesting histamine H-receptor1 antagonists were introduced in the late 1940s and early 1950s. Several H-antihistaminics have a similar cardiac effect to that seen with astemizole1 and terfenadine. Serious cardiovascular adverse reactions have been reported when used concomitantly with imidazole antifungals and macrolide antibiotics. See also under astemizole.

You can find Terfenadine suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.