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ChemicalBook >> CAS DataBase List >>Zopiclone

Zopiclone suppliers

Zopiclone

CAS:
43200-80-2
MF:
C17H17ClN6O3
MW:
388.81

Company Type

Properties

Melting point:
1780C
Boiling point:
580.7±50.0 °C(Predicted)
Density 
1.1105 (estimate)
Flash point:
2℃
storage temp. 
Store at RT
solubility 
DMSO: 2 mg/mL
form 
Solid
pka
pKa ﹣1.5±0.1(10% ACN in aq. H2SO4 t = 25.0) (Uncertain)
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
GBBSUAFBMRNDJC-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302-H336
Precautionary statements 
P261-P264-P270-P271-P301+P312-P304+P340+P312
Hazard Codes 
Xn,Xi,F
Risk Statements 
20/21/22-36/37/38-62-36-11
Safety Statements 
26-36-36/37-16
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
TL1425000
HS Code 
29339900
Toxicity
mouse,LD50,intramuscular,541mg/kg (541mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Oyo Yakuri. Pharmacometrics. Vol. 26, Pg. 935, 1983.

Use

Zopiclone is an agonist at the type A -aminobutyric acid (GABA) receptor. It is a non-benzodiazepine hypnotic which was first reviewed in Drugs in 1986 and it is indicated for short-term treatment of insomnia. Zopiclone has a relatively low propensity to cause residual clinical effects (such as difficulty in waking or reduced morning concentration).

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