Doxycycline manufacturers and suppliers

Doxycycline suppliers

Properties

Melting point:: 206-209°C (dec.)

Boiling point:: 554.44°C (rough estimate)

Density: 1.3809 (rough estimate)

refractive index: 1.6500 (estimate)

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C

solubility: DMSO : 125 mg/mL (281.26 mM; Need ultrasonic)

pka: pKa 3.5 (Uncertain);7.7 (Uncertain);9.5 (Uncertain)

form: Solid

color: Light yellow to brown

Water Solubility: 0.63g/L(25 ºC)

BCS Class: 3,1

InChIKey: JBIWCJUYHHGXTC-AKNGSSGZSA-N

SMILES: C1(=O)[C@]2(O)[C@@]([H])([C@@H](O)[C@@]3([H])C(=C2O)C(=O)C2=C(C=CC=C2O)[C@@H]3C)[C@H](N(C)C)C(O)=C1C(N)=O

CAS DataBase Reference: 564-25-0(CAS DataBase Reference)

EPA Substance Registry System: Doxycycline (564-25-0)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H312-H319-H335-H332

Precautionary statements: P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P

Hazardous Substances Data: 564-25-0(Hazardous Substances Data)

Use

Doxycycline is a semi-synthetic tetracycline prepared by hydrogenolysis of oxytetracycline to remove the 6-hydroxy group. Although the synthesis was reported in 1958, it was not released for use until 1967. Doxycycline, together with minocycline, is regarded as a ‘third generation’ tetracycline largely replacing the analogues and pro-drugs produced in the early 1960s for mainstream antibiotic applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Doxycycline has been extensively cited in the literature with over 10,000 references.

You can find Doxycycline suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.