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EHT1864

CAS:
754240-09-0
MF:
C25H27F3N2O4S2HCl
MW:
0

Properties

Melting point:
>195°C (dec.)
storage temp. 
2-8°C
solubility 
H2O: soluble10mg/mL, clear
form 
powder
color 
white to beige

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302-H315-H319-H335
Precautionary statements 
P261-P305+P351+P338
WGK Germany 
3

Use

EHT 1864 is an inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively. It can reverse transformation of NIH 3T3 fibroblasts caused by constitutively activated Rac1, as well as Rac-dependent transformation caused by Tiam1 or Ras. EHT 1864 inhibits APP processing by γ-secretase, reducing Αβ40 and Αβ42 accumulation. It blocks breast cancer cell invasion in a collagen matrix assay and, at 10 μM, increases the size but decreases the density of dendritic spines of hippocampal neurons in culture.

72 supplier list of "EHT1864"

  • Product Name:5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
  • Company Type: Reagent
  • Country/Region: CHINA

    $1.00/ 1KG

  • Product Name: EHT 1864
  • Products Intro:Purity: Min98% HPLC | Package: 1KG;1USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:EHT1864
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride
  • Products Intro:Purity: 98% | Package: 100G, 5KG, 25KG or as request | CustNote: Commercial stage
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: fluorinated aromatics,fluorinated pyridine,heterocyclic compounds,non-natural amino acids
  • Product Name:EHT 1864
  • Products Intro:Purity: NLT 98% | CustNote: MC570347
  • Company Type: Manufacturer
  • Country/Region: CHINA
  • Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
  • Product Name:EHT 1864;EHT 1864 2HCl
  • Products Intro:Package: 1 mL * 10mM (in DMSO);10 mg;2 mg;25 mg;5 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • 5mg$98.00
    10mg$150.00
    25mg$239.00
    50mg$400.00
    100mg$650.00
    250mg$1150.00
    500mg$1750.00
  • Product Name:EHT18642HCl
  • Products Intro:Brand:InvivoChem | Product Number:V1566 | Purity:≥98%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:EHT-1864 2HCl
  • Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A865685
  • Company Type: Reagent
  • Country/Region: CHINA
  • 10mg$535.00
  • Product Name:EHT 1864
  • Products Intro:Brand: Sigma-Aldrich | Product Number: E1657 | Purity: ≥98% (HPLC)
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: fluorinated aromatics,fluorinated pyridine,heterocyclic compounds,non-natural amino acids
  • 1 mg$25.00
    5 mg$99.00
    10 mg$175.00
    50 mg$750.00
  • Product Name:EHT 1864
  • Products Intro:Brand: Caymanchem | Product Number: 17258 | Purity: ≥98%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: fluorinated aromatics,fluorinated pyridine,heterocyclic compounds,non-natural amino acids

EHT1864 Related Search:

MG-132FulvestrantN4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-Morpholin-4-yl-propyl)-pyriMidine-2,4-diaMineML 141NSC 23766 (hydrochloride)ABT 263
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