Erythromycin Estolate manufacturers and suppliers

Erythromycin Estolate suppliers

Properties

Melting point:: 135-140°C dec.

Boiling point:: 743℃

Density: 1.0053 (rough estimate)

refractive index: 1.6550 (estimate)

Flash point:: >110°(230°F)

storage temp.: Keep in dark place,Sealed in dry,Room Temperature

solubility: chloroform: soluble4.0ML, clear, colorless (200 mg + 4.0 mL Chloroform)

pka: 6.9(at 25℃)

color: white

Water Solubility: Freely soluble in organic solvents, practically insoluble in water /n

Sensitive: Light Sensitive

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Danger

Hazard statements: H302-H317-H334

Precautionary statements: P261-P264-P280-P301+P312-P302+P352-P304+P340+P312

Hazard Codes: Xn,Xi

Risk Statements: 22-42/43-36/37/38

Safety Statements: 22-36-26

WGK Germany: 3

RTECS: KF5775000

HS Code: 29419000

Toxicity: LD50 orally in rats: >5000 mg/kg (Goldenthal)

Use

Erythromycin estolate, erythromycin propionate lauryl sulfate(Ilosone), is the lauryl sulfate salt of the 2＇-propionateester of erythromycin. Erythromycin estolate is acid stableand absorbed as the propionate ester. The ester undergoesslow hydrolysis in vivo. Only the free base binds to bacterialribosomes. Some evidence, however, suggests that theester is taken up by bacterial cells more rapidly than thefree base and undergoes hydrolysis by bacterial esteraseswithin the cells. The incidence of cholestatic hepatitis is reportedlyhigher with the estolate than with other erythromycinpreparations.Erythromycin estolate occurs as long needles that aresparingly soluble in water but soluble in organic solvents. administration for the treatment of serious infections,such as Legionnaires disease, or when oral administrationis not possible. Solutions are stable for 1 week whenrefrigerated.

You can find Erythromycin Estolate suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.