Halothane manufacturers and suppliers

Halothane suppliers

Properties

Melting point:: -115.75°C

Boiling point:: 50.2 °C(lit.)

Density: 1.872 g/mL at 25 °C(lit.)

vapor pressure: 4.5 psi ( 20 °C)

refractive index: n20/D 1.369(lit.)

Flash point:: 49-50°C

storage temp.: 2-8°C

solubility: Slightly soluble in water, miscible with anhydrous ethanol and with trichloroethylene.

form: Colorless liquid

color: Colorless to light yellow

Water Solubility: Soluble in water (8 mg/ml).

Sensitive: Light Sensitive

Merck: 14,4603

BRN: 1736947

Henry's Law Constant: 5.6×10^-4 mol/(m³Pa) at 25℃, Fogg and Sangster (2003)

Exposure limits: TLV-TWA 50 ppm (～400 mg/m³) (ACGIH).

InChI: 1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H

InChIKey: BCQZXOMGPXTTIC-UHFFFAOYSA-N

SMILES: FC(F)(F)C(Cl)Br

CAS DataBase Reference: 151-67-7(CAS DataBase Reference)

EPA Substance Registry System: Halothane (151-67-7)

Safety Information

Symbol(GHS): GHS05,GHS07,GHS08

Signal word: Danger

Hazard statements: H315-H318-H335-H360

Precautionary statements: P201-P280-P305+P351+P338+P310-P308+P313

target organs: Respiratory system

PPE: Eyeshields, Gloves

Hazard Codes: T,Xi,Xn

Risk Statements: 61-37/38-41-40-20

Safety Statements: 53-23-26-36/37-45-36

RIDADR: UN 3334

OEL: Ceiling: 2 ppm (16.2 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]

WGK Germany: 3

RTECS: KH6550000

F: 8-19

Hazard Note: Irritant

HS Code: 2937990000

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Eye Dam. 1
Repr. 1B
Skin Irrit. 2
STOT SE 3

Hazardous Substances Data: 151-67-7(Hazardous Substances Data)

Toxicity: LD50 oral in rat: 5680mg/kg

Use

Halothane is a nonflammable, nonpungent, volatile, liquid,halogenated (F, Cl, and Br) ethane (bp＝50°C), introducedin 1956. Halothane may increase heart rate, cause cardiacarrhythmias, increase cerebral blood flow, and increase intracranialpressure.It can undergo spontaneous oxidationwhen exposed to ultraviolet light to yield HCl, HBr, Cl ,Br- , and phosgene (COCl2). To prevent oxidation it ispackaged in amber bottles with a low concentration of thymol(0.01%) as a stabilizer. The drug has a high potency(MAC＝0.75%), a blood:gas partition coefficient of 2.4,and high adipose solubility. Halothane undergoes both reductiveand oxidative processes with up to 20% of the doseundergoing metabolism .The trifluoroacetylchloride metabolite is electrophilic and can form covalentbonds with proteins leading to immune responses andhalothane hepatitis upon subsequent halothane exposure.Halothane hepatitis is rare with 1 case reported for every6,000 to 35,000 patients exposed.

You can find Halothane suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.