Levodopa manufacturers and suppliers

Levodopa suppliers

Properties

Melting point:: 276-278 °C (lit.)

Boiling point:: 334.28°C (rough estimate)

alpha: -11.7 º (c=5.3, 1N HCl)

Density: 1.3075 (rough estimate)

refractive index: -12 ° (C=5, 1mol/L HCl)

storage temp.: 2-8°C

solubility: Slightly soluble in water, practically insoluble in ethanol (96 per cent). It is freely soluble in 1 M hydrochloric acid and sparingly soluble in 0.1 M hydrochloric acid .

pka: 2.32(at 25℃)

form: Crystalline Powder

color: White to creamy

Odor: at 100.00 %. odorless

Odor Type: odorless

optical activity: -39.5 (H2O) -12.025 (1 mol dm-3 HCl)

Water Solubility: Slightly soluble in water, dilute hydrochloric acid and formic acid. Insoluble in ethanol.

Merck: 14,5464

BRN: 2215169

Stability:: Stable. Incompatible with strong oxidizing agents. Light and air sensitive.

Major Application: peptide synthesis

InChI: 1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChIKey: WTDRDQBEARUVNC-LURJTMIESA-N

SMILES: N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O

LogP: -1.154 (est)

CAS DataBase Reference: 59-92-7(CAS DataBase Reference)

NIST Chemistry Reference: Levodopa(59-92-7)

EPA Substance Registry System: Levodopa (59-92-7)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

target organs: Respiratory system

PPE: dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes: Xn

Risk Statements: 22-36/37/38-20/21/22

Safety Statements: 26-36-24/25

WGK Germany: 3

RTECS: AY5600000

F: 10-23

TSCA: TSCA listed

HS Code: 29225090

Storage Class: 11 - Combustible Solids

Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Hazardous Substances Data: 59-92-7(Hazardous Substances Data)

Toxicity: LD50 in mice (mg/kg): 3650 ±327 orally, 1140 ±66 i.p., 450 ±42 i.v., >400 s.c.; in male, female rats (mg/kg): >3000, >3000 orally; 624, 663 i.p.; >1500, >1500 s.c. (Clark)

REACH Registrations: Active

Use

Levodopa is typically prescribed to a patient with Parkinson's disease once symptoms become more difficult to control with other anti-Parkinsonism drugs. The drug can also be used for postencephalitic Parkinsonism and symptomatic Parkinsonism due to carbon monoxide intoxication.

You can find Levodopa suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.