LUFFARIELLOLIDE suppliers
LUFFARIELLOLIDE
- CAS:
- 111149-87-2
- MF:
- C25H38O3
- MW:
- 386.57
Suppliers by country/region
Properties
- Boiling point:
- 541.7±50.0 °C(Predicted)
- Density
- 1.006±0.06 g/cm3(Predicted)
- solubility
- DMSO: soluble; Ethanol: soluble
- pka
- 9.98±0.40(Predicted)
- form
- Pale yellow oil.
- InChI
- InChI=1S/C25H38O3/c1-18(11-7-13-21-17-23(26)28-24(21)27)9-6-10-19(2)14-15-22-20(3)12-8-16-25(22,4)5/h10-11,17,24,27H,6-9,12-16H2,1-5H3/b18-11+,19-10+
- InChIKey
- JPWPYTMXSXYUPG-QZPYEDBESA-N
- SMILES
- O1C(O)C(CC/C=C(\C)/CC/C=C(\C)/CCC2C(C)(C)CCCC=2C)=CC1=O
Safety Information
Use
Luffariellolide is a natural sesterterpenoid which reversibly inhibits secretory phospholipase A2 isoforms from bee venom (IC50 = 230 nM) and snake venom, reducing inflammation. It blocks the production of platelet-activating factor in stimulated neutrophils (IC50 = 5 μM). Luffariellolide is also a structural mimic of all-trans retinoic acid (RA) and, at 1 μM, acts as an agonist for the RA receptors RAR α, β, and γ but not for other nuclear receptors. In RA-sensitive cancer cell lines, luffariellolide induces the expression of RAR target genes and inhibits cell growth. It also inhibits the activation of hypoxia-inducible factor by hypoxia (IC50 = 3.6 μM).[Cayman Chemical]
38 supplier list of "LUFFARIELLOLIDE"
- Product Name:Luffariellolide
- Products Intro:Purity: 0.98 | Package: 100mg;1g;500g | CustNote: Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediates,raw materials,small molecule inhibitors,food additives,Biochemical reagents
- Product Name:Luffariellolide
- Products Intro:Purity: >=98% | Package: $147.9/1mg;$662.9/5mg;$1192.9/10mg;$2683.9/25mg;$4830.9/50mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
-
1 mg$120.00
- Product Name:Luffariellolide
- Products Intro:Brand: Caymanchem | Product Number: 14902 | Purity: ≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof
-
1mg$293.00
- Products Intro:Brand:1pchem | Product Number:1P01E6JG | Purity:≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Luffariellolide
- Products Intro:Brand：a2bchem | Product Number：AX40476 | Purity：≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
-
1mg$262.00
- Product Name:Luffariellolide
- Products Intro:Brand：aksci | Product Number：1118CP
- Company Type: Trader
- Country/Region: UNITED STATES
-
1mg$690.00
- Product Name:Luffariellolide
- Products Intro:Brand:trc-canada | Product Number:L473753
- Company Type: Trader
- Country/Region: CANADA
-
500ug$708.00
- Product Name:Luffariellolide
- Products Intro:Brand：Usbio | OriginalID：453957
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:LUFFARIELLOLIDE
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:LUFFARIELLOLIDE
- Company Type: Trader
- Country/Region: CHINA