Sulfamethoxypyridazine manufacturers and suppliers

Sulfamethoxypyridazine suppliers

Properties

Melting point:: 182-183°

Boiling point:: 564.9±60.0 °C(Predicted)

Density: 1.3936 (rough estimate)

refractive index: 1.6200 (estimate)

storage temp.: 2-8°C

solubility: DMSO (Slightly), Methanol (Slightly)

form: Crystalline Powder

pka: 6.7(at 25℃)

color: White to yellow

Water Solubility: 579.5mg/L(25 ºC)

Merck: 14,8919

BRN: 277076

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H317-H334

Precautionary statements: P261-P272-P280-P284-P302+P352-P333+P313

Hazard Codes: Xi

Risk Statements: 37/38-41

Safety Statements: 26-39

WGK Germany: 2

RTECS: WP0400000

F: 10

HS Code: 29350090

Toxicity: LD50 orally in mice: 1750 mg/kg, (Seki)

Use

Sulfamethoxypyridazine, a sulfonamide anti-infective agent, was introduced in 1957 for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Commercial manufacture of the drug has been discontinued by at least one major manufacturer but supplies can still be obtained on special request, particularly for patients with dermatitis herpetiformis in which condition it has been claimed to be beneficial.

You can find Sulfamethoxypyridazine suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.