Trospium Chloride manufacturers and suppliers

Trospium chloride suppliers

Properties

Melting point:: 266-268°C

storage temp.: Inert atmosphere,2-8°C

solubility: Very soluble in water, freely soluble in methanol, practically insoluble in methylene chloride.

form: Solid

color: White to Off-White

Merck: 14,9786

InChIKey: RVCSYOQWLPPAOA-QKYUOBHYSA-M

SMILES: [N+]12(CCCC1)[C@@]1([H])CC[C@]2([H])C[C@@H](C1)OC(=O)C(O)(C1=CC=CC=C1)C1C=CC=CC=1.[Cl-] |&1:5,9,12,r|

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

RTECS: WH1424000

HS Code: 2939800000

Toxicity: Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler)

Use

Trospium chloride is a quaternary ammonium compound that is nonselective for the muscarinic receptor. It also has smooth muscle relaxant qualities.(Staskin et al.，2007) Trospium chloride is available in an lR formulation given 20 mg twice daily or an ER formula administered 60 mg daily. The uniqueness of this antimuscarinic is that it is renally cleared.Care should be used in the elderly and patients with renal impairment. The initial dosing in these patients she be the IR formulation 20 mg once daily. The ER formulation should not be used in patients with severe renal impairment. Because of poor bioavailability, trospium chloride must be taken on an empty stomach.

You can find Trospium chloride suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.