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ChemicalBook >> CAS DataBase List >> 1-(1-Naphthyl)piperazine hydrochloride

1-(1-Naphthyl)piperazine hydrochloride

1-(1-Naphthyl)piperazine hydrochloride price.
  • $40 - $1186.07
  • Product name: 1-(1-Naphthyl)piperazine hydrochloride
  • CAS: 104113-71-5
  • MF: C14H17ClN2
  • MW: 248.75
  • EINECS:
  • MDL Number:MFCD00055161
  • Synonyms:1-(1-NAPHTHYL)PIPERAZINE;1-(1-NAPHTHYL)PIPERAZINE HCL;1-(1-Naphthalenyl)piperazine;1-(Piperazin-1-yl)naphthalene;1-(Naphthalen-1-yl)piperazineHCl;1-(1-Naphthyl)piperazine*2HCl;Piperazine, 1-(1-naphthalenyl)-, hydrochloride (1:1);TIMTEC-BB SBB003161
Price33 Properties Safety Information Description
33 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Activate Scientific
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • Thermo Scientific Chemicals
  • TRC
Package
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1.00g
  • 1000mg
  • 1G
  • 5.00g
  • 5G
  • 50g
  • Manufactureraablocks
  • Product numberAA00HA7H
  • Product description1-(Naphthalen-1-yl)piperazine hydrochloride
  • Packaging10mg
  • Price$45
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00HA7H
  • Product description1-(Naphthalen-1-yl)piperazine hydrochloride
  • Packaging250mg
  • Price$53
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238450
  • Product description1-(1-Naphthyl) piperazine hydrochloride 98%
  • Packaging250MG
  • Price$315
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238450
  • Product description1-(1-Naphthyl) piperazine hydrochloride 98%
  • Packaging1G
  • Price$625
  • Updated2026-05-27
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS210618
  • Product description1-(Naphth-1-yl)piperazine diHCl 96%
  • Packaging1g
  • Price$268
  • Updated2026-06-04
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS210618
  • Product description1-(Naphth-1-yl)piperazine diHCl 96%
  • Packaging250mg
  • Price$100
  • Updated2026-06-04
  • Buy
  • ManufacturerAHH
  • Product numberMT-19400
  • Product description1-(1-Naphthyl)piperazine hydrochloride 97%
  • Packaging50g
  • Price$788
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product number1778CH
  • Product description1-(1-Naphthyl)piperazine hydrochloride
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1778CH
  • Product description1-(1-Naphthyl)piperazine hydrochloride
  • Packaging100mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0006880
  • Product description1-NAPHTHALEN-1-YLPIPERAZINE HYDROCHLORIDE 95.00%
  • Packaging5G
  • Price$1186.07
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0006880
  • Product description1-NAPHTHALEN-1-YLPIPERAZINE HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$754.33
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3828
  • Product description1-(1-Naphthyl) piperazine (hydrochloride)
  • Packaging250mg
  • Price$689
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3828
  • Product description1-(1-Naphthyl) piperazine (hydrochloride)
  • Packaging100mg
  • Price$298
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3828
  • Product description1-(1-Naphthyl) piperazine (hydrochloride)
  • Packaging50mg
  • Price$158
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3828
  • Product description1-(1-Naphthyl) piperazine (hydrochloride)
  • Packaging25mg
  • Price$99
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberFN65693
  • Product description1-(1-Naphthyl)piperazine hydrochloride
  • Packaging50mg
  • Price$150
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00HA7H 1-(Naphthalen-1-yl)piperazine hydrochloride 10mg $45 2026-05-28 Buy
aablocks AA00HA7H 1-(Naphthalen-1-yl)piperazine hydrochloride 250mg $53 2026-05-28 Buy
ACHEMBLOCK Z238450 1-(1-Naphthyl) piperazine hydrochloride 98% 250MG $315 2026-05-27 Buy
ACHEMBLOCK Z238450 1-(1-Naphthyl) piperazine hydrochloride 98% 1G $625 2026-05-27 Buy
Activate Scientific AS210618 1-(Naphth-1-yl)piperazine diHCl 96% 1g $268 2026-06-04 Buy
Activate Scientific AS210618 1-(Naphth-1-yl)piperazine diHCl 96% 250mg $100 2026-06-04 Buy
AHH MT-19400 1-(1-Naphthyl)piperazine hydrochloride 97% 50g $788 2026-05-26 Buy
AK Scientific 1778CH 1-(1-Naphthyl)piperazine hydrochloride 25mg $160 2021-12-16 Buy
AK Scientific 1778CH 1-(1-Naphthyl)piperazine hydrochloride 100mg $318 2021-12-16 Buy
American Custom Chemicals Corporation CHM0006880 1-NAPHTHALEN-1-YLPIPERAZINE HYDROCHLORIDE 95.00% 5G $1186.07 2021-12-16 Buy
American Custom Chemicals Corporation CHM0006880 1-NAPHTHALEN-1-YLPIPERAZINE HYDROCHLORIDE 95.00% 1G $754.33 2021-12-16 Buy
ApexBio Technology C3828 1-(1-Naphthyl) piperazine (hydrochloride) 250mg $689 2026-05-06 Buy
ApexBio Technology C3828 1-(1-Naphthyl) piperazine (hydrochloride) 100mg $298 2026-05-06 Buy
ApexBio Technology C3828 1-(1-Naphthyl) piperazine (hydrochloride) 50mg $158 2026-05-06 Buy
ApexBio Technology C3828 1-(1-Naphthyl) piperazine (hydrochloride) 25mg $99 2026-05-06 Buy
Biosynth FN65693 1-(1-Naphthyl)piperazine hydrochloride 50mg $150 2026-06-04 Buy
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Properties

Melting point :235-237 °C
storage temp. :Store at -20°C
solubility :H2O: soluble
form :needles
color :white
InChI :InChI=1S/C14H16N2.ClH/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16;/h1-7,15H,8-11H2;1H
InChIKey :ZYVYPNZFOCZLEM-UHFFFAOYSA-N
SMILES :C1(C=CC=C2C=CC=CC=12)N1CCNCC1.Cl

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

1-(1-Naphthyl) piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. 1-NP also blocks contraction in the rat fundus induced by either 5-HT or tryptamine (IC50 = 1 nM for both agonists). 1-NP mimics the 5-HT1 agonist 1-(m-trifluoromethylphenyl)piperazine (TFMPP, ) in decreasing 5-HT receptor turnover and increasing serum corticosterone, suggesting that, in the absence of 5-HT, 1-NP may act as an agonist of the 5-HT1 receptor. However, in squirrel monkeys, 1-NP acts as a non-selective 5-HT receptor antagonist in altering operant behavior. 1-NP also binds to the human 5-HT6 receptor with an affinity comparable to that of 5-HT (Kis = 120 and 100 nM, respectively).

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