Halofuginone Hydrochloride
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- $75 - $660
- Product name: Halofuginone Hydrochloride
- CAS: 1217623-74-9
- MF: C16H18BrCl2N3O3
- MW: 451.14242
- EINECS:
- MDL Number:MFCD09839202
- Synonyms:Halofuginone HCl;4(3H)-Quinazolinone, 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-, hydrochloride (1:1), rel-
13 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- TRC
Package
- 100ug
- 250ug
- 500μg
- 500ug
- 0.5MG
- 1MG
- 2mg
- 5MG
- 10mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000588
- Product descriptionHALOFUGINONE HYDROCHLORIDE 95.00%
- Packaging0.5MG
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000588
- Product descriptionHALOFUGINONE HYDROCHLORIDE 95.00%
- Packaging1MG
- Price$560
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000588
- Product descriptionHALOFUGINONE HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23732
- Product descriptionHalofuginone hydrochloride
- Packaging100ug
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23732
- Product descriptionHalofuginone hydrochloride
- Packaging250ug
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23732
- Product descriptionHalofuginone hydrochloride
- Packaging500ug
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23732
- Product descriptionHalofuginone hydrochloride
- Packaging1mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23732
- Product descriptionHalofuginone hydrochloride
- Packaging2mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13370
- Product descriptionHalofuginone (hydrochloride) ≥95%
- Packaging500μg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13370
- Product descriptionHalofuginone (hydrochloride) ≥95%
- Packaging1mg
- Price$218
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13370
- Product descriptionHalofuginone (hydrochloride) ≥95%
- Packaging5mg
- Price$481
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberH102500
- Product descriptionHalofuginoneHydrochloride
- Packaging5mg
- Price$305
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberH102500
- Product descriptionHalofuginoneHydrochloride
- Packaging10mg
- Price$490
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0000588 | HALOFUGINONE HYDROCHLORIDE 95.00% | 0.5MG | $480 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000588 | HALOFUGINONE HYDROCHLORIDE 95.00% | 1MG | $560 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000588 | HALOFUGINONE HYDROCHLORIDE 95.00% | 5MG | $660 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH23732 | Halofuginone hydrochloride | 100ug | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH23732 | Halofuginone hydrochloride | 250ug | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH23732 | Halofuginone hydrochloride | 500ug | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH23732 | Halofuginone hydrochloride | 1mg | $320 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH23732 | Halofuginone hydrochloride | 2mg | $400 | 2021-12-16 | Buy |
| Cayman Chemical | 13370 | Halofuginone (hydrochloride) ≥95% | 500μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 13370 | Halofuginone (hydrochloride) ≥95% | 1mg | $218 | 2024-03-01 | Buy |
| Cayman Chemical | 13370 | Halofuginone (hydrochloride) ≥95% | 5mg | $481 | 2024-03-01 | Buy |
| TRC | H102500 | HalofuginoneHydrochloride | 5mg | $305 | 2021-12-16 | Buy |
| TRC | H102500 | HalofuginoneHydrochloride | 10mg | $490 | 2021-12-16 | Buy |
Properties
Melting point :247-249°C (dec.)
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble; Water: soluble
form :A crystalline solid
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble; Water: soluble
form :A crystalline solid
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga. It has antimalarial and anticoccidial actions. In mammals, halofuginone at 10 ng/ml down-regulates Smad3, blocking TGF-β signaling and preventing both the differentiation of fibroblasts to myofibroblasts and the transitioning of epithelial cells to mesenchymal cells. Through this action, halofuginone blocks fibrosis and tumor progression in a variety of different models. This compound also competitively inhibits prolyl-tRNA synthetase (Ki = 18.3 nM), activating the amino acid starvation response. This prevents the differentiation of TH17 cells, blunting an autoimmune response.More related product prices
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