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ChemicalBook >> CAS DataBase List >> (1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-D3)phenyl]-1,4,6-heptatrien-3-one

(1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-D3)phenyl]-1,4,6-heptatrien-3-one

(1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-D3)phenyl]-1,4,6-heptatrien-3-one price.
Price6 Properties Safety Information Description
6 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA01DF26
  • Product description(1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-d3)phenyl]-1,4,6-heptatrien-3-one ≥99%deuteratedforms(d1-d6)
  • Packaging1mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA01DF26
  • Product description(1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-d3)phenyl]-1,4,6-heptatrien-3-one ≥99%deuteratedforms(d1-d6)
  • Packaging5mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0353EB
  • Product description(1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(trideuteriomethoxy)phenyl]hepta-1,4,6-trien-3-one
  • Packaging100mg
  • Price$863
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25438
  • Product descriptionCurcumin-d6 ≥99% deuterated forms (d1-d6)
  • Packaging500μg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25438
  • Product descriptionCurcumin-d6 ≥99% deuterated forms (d1-d6)
  • Packaging1mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25438
  • Product descriptionCurcumin-d6 ≥99% deuterated forms (d1-d6)
  • Packaging5mg
  • Price$336
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01DF26 (1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-d3)phenyl]-1,4,6-heptatrien-3-one ≥99%deuteratedforms(d1-d6) 1mg $205 2021-12-16 Buy
aablocks AA01DF26 (1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(methoxy-d3)phenyl]-1,4,6-heptatrien-3-one ≥99%deuteratedforms(d1-d6) 5mg $395 2021-12-16 Buy
AK Scientific 0353EB (1E,4Z,6E)-5-Hydroxy-1,7-bis[4-hydroxy-3-(trideuteriomethoxy)phenyl]hepta-1,4,6-trien-3-one 100mg $863 2021-12-16 Buy
Cayman Chemical 25438 Curcumin-d6 ≥99% deuterated forms (d1-d6) 500μg $81 2024-03-01 Buy
Cayman Chemical 25438 Curcumin-d6 ≥99% deuterated forms (d1-d6) 1mg $152 2024-03-01 Buy
Cayman Chemical 25438 Curcumin-d6 ≥99% deuterated forms (d1-d6) 5mg $336 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :0.1 M NaOH: >3 mg/ml; Acetone: >20 mg/ml
form :A solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin by GC- or LC-MS. Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities.1,2,3,4 It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.1 Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells.2 In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; ) in mouse skin.3 Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.4

Suppliers and manufacturers

Accela ChemBio Inc. Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Energy Chemical Shanghai Yiyan Biotechnology Co. , Ltd. Shanghai Yifei Biotechnology Co. , Ltd. Accela ChemBio Co.,Ltd.