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ChemicalBook >> CAS DataBase List >> Bisindolylmaleimide VIII acetate salt

Bisindolylmaleimide VIII acetate salt

Bisindolylmaleimide VIII acetate salt price.
  • $45 - $478
  • Product name: Bisindolylmaleimide VIII acetate salt
  • CAS: 138516-31-1
  • MF: C24H22N4O2
  • MW: 398.464
  • EINECS:
  • MDL Number:MFCD00909467
  • Synonyms:BisindolylMaleiMide VIII . AcOH [Ro 31-7549];BISINDOLYLMALEIMIDE VIII ACETATE SALT;RO 31-7549 ACETATE;3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione monoacetate;Bis VIII acetate;1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-, acetate (1:1);protein,Bisindolylmaleimide VIII acetate,Ro 31-7549,Inhibitor,inhibit,Fas,Bis VIII,Apoptosis,autoimmune,Protein kinase C,diseases,kinase,cell-mediated,Bisindolylmaleimide VIII,PKC
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0114-M001
  • Product descriptionBisindolylmaleimideVIII.acetate ≥98%(NMR)
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0114-M005
  • Product descriptionBisindolylmaleimideVIII.acetate ≥98%(NMR)
  • Packaging5mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3821CR
  • Product descriptionBisindolylmaleimideVIII
  • Packaging5mg
  • Price$301
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3821CR
  • Product descriptionBisindolylmaleimideVIII
  • Packaging10mg
  • Price$478
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4315
  • Product descriptionBisindolylmaleimideVIII(acetate)
  • Packaging5mg
  • Price$207
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4315
  • Product descriptionBisindolylmaleimideVIII(acetate)
  • Packaging10mg
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13333
  • Product descriptionBisindolylmaleimide VIII (acetate) ≥98%
  • Packaging1mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13333
  • Product descriptionBisindolylmaleimide VIII (acetate) ≥98%
  • Packaging5mg
  • Price$183
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13333
  • Product descriptionBisindolylmaleimide VIII (acetate) ≥98%
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0115630
  • Product descriptionBisindolylmaleimideVIII(acetate)
  • Packaging5mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB448500
  • Product descriptionBisindolylmaleimideVIIIAceticAcidSalt
  • Packaging10mg
  • Price$175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0114-M001 BisindolylmaleimideVIII.acetate ≥98%(NMR) 1mg $45 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-0114-M005 BisindolylmaleimideVIII.acetate ≥98%(NMR) 5mg $170 2021-12-16 Buy
AK Scientific 3821CR BisindolylmaleimideVIII 5mg $301 2021-12-16 Buy
AK Scientific 3821CR BisindolylmaleimideVIII 10mg $478 2021-12-16 Buy
ApexBio Technology C4315 BisindolylmaleimideVIII(acetate) 5mg $207 2021-12-16 Buy
ApexBio Technology C4315 BisindolylmaleimideVIII(acetate) 10mg $389 2021-12-16 Buy
Cayman Chemical 13333 Bisindolylmaleimide VIII (acetate) ≥98% 1mg $50 2024-03-01 Buy
Cayman Chemical 13333 Bisindolylmaleimide VIII (acetate) ≥98% 5mg $183 2024-03-01 Buy
Cayman Chemical 13333 Bisindolylmaleimide VIII (acetate) ≥98% 10mg $341 2024-03-01 Buy
ChemScene CS-0115630 BisindolylmaleimideVIII(acetate) 5mg $260 2021-12-16 Buy
TRC B448500 BisindolylmaleimideVIIIAceticAcidSalt 10mg $175 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :Soluble in DMSO
form :Red powder.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Bisindolylmaleimide VIII (BIM VIII) is a selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. This compound exhibits some degree of PKC isozyme specificity with preference for PKCα over PKCβI, PKCβII, PKCγ, or PKCε (IC50s = 53, 195, 163, 213, and 175 nM, respectively). At 10 μM BIM VIII does not inhibit the tyrosine phosphorylation or the activation of phospholipase C γ1. BIM VIII inhibits carbachol-evoked noradrenaline release from human SH-SY5Y neuroblastoma cells with an IC50 value of 600 nM.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Hangzhou MolCore BioPharmatech Co.,Ltd.
Aladdin Scientific J & K SCIENTIFIC LTD. Sichuan Wei Keqi Biological Technology Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Rechem science Co., Ltd. Shanghai Chaolan Chemical Technology Center Beijing Jin Ming Biotechnology Co., Ltd.