BISINDOLYLMALEIMIDE VII
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- $122 - $496.72
- Product name: BISINDOLYLMALEIMIDE VII
- CAS: 137592-47-3
- MF: C27H27N5O2
- MW: 453.54
- EINECS:
- MDL Number:MFCD01076634
- Synonyms:BISINDOLYLMALEIMIDE VII;1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[3-(1-piperazinyl)propyl]-1H-indol-3-yl]-
3 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Sigma-Aldrich
Package
- 1MG
- 5MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPRK0000426
- Product descriptionBISINDOLYLMALEIMIDE VII 95.00%
- Packaging1MG
- Price$171.15
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPRK0000426
- Product descriptionBISINDOLYLMALEIMIDE VII 95.00%
- Packaging5MG
- Price$496.72
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberB3681
- Product descriptionBisindolylmaleimide VII 96% (TLC), solid
- Packaging1mg
- Price$122
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | PRK0000426 | BISINDOLYLMALEIMIDE VII 95.00% | 1MG | $171.15 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PRK0000426 | BISINDOLYLMALEIMIDE VII 95.00% | 5MG | $496.72 | 2021-12-16 | Buy |
| Sigma-Aldrich | B3681 | Bisindolylmaleimide VII 96% (TLC), solid | 1mg | $122 | 2024-03-01 | Buy |
Properties
Boiling point :761.6±60.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: soluble
form :solid
pka :8.18±0.60(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: soluble
form :solid
pka :8.18±0.60(Predicted)
Safety Information
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Description
Bisindolylmaleimides are potent, selective inhibitors of protein kinase C (PKC). They are structurally similar to the naturally occurring molecule, staurosporine, but they are more selective for PKC over other protein kinases. Bisindolylmaleimides are used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals. Bisindolylmaleimides inhibit PKC by interacting with the catalytic subunit. Inhibition is competitive with ATP. Studies of structure-activity relationships of analogs indicate that cationic substituents at the indole nitrogen increase the potency as an inhibitor of PKC.Related product price
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