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ChemicalBook >> CAS DataBase List >> GF109203X

GF109203X

GF109203X price.
  • $28 - $4335
  • Product name: GF109203X
  • CAS: 133052-90-1
  • MF: C25H24N4O2
  • MW: 412.48
  • EINECS:
  • MDL Number:MFCD00236428
  • Synonyms:Bisindolylmaleimide I (GF 109203X);InSolution? Bisindolylmaleimide I ;GO 6850;GO 6850 HCL;GF 109203X;GF-109203X HCL;GF109203X HYDROCHLORIDE;BISINDOLYLMALEIMIDE
50 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 250μg
  • 2.5mg
  • 10mg
  • 250mg
  • 1ml
  • 1000mg
  • 1
  • 10
  • 1mg
  • 1unit
  • 5mg
  • 25mg
  • 50mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0009-M001
  • Product descriptionBisindolylmaleimide I ≥97%(NMR)
  • Packaging1mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1641AH
  • Product descriptionBisindolylmaleimide I
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63401
  • Product descriptionBisindolylmaleimide 1
  • Packaging5mg
  • Price$153.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63401
  • Product descriptionBisindolylmaleimide 1
  • Packaging25mg
  • Price$421.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA439059
  • Product descriptionBisindolylmaleimide I 98+%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA439059
  • Product descriptionBisindolylmaleimide I 98+%
  • Packaging25mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA439059
  • Product descriptionBisindolylmaleimide I 98+%
  • Packaging50mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA439059
  • Product descriptionBisindolylmaleimide I 98+%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA439059
  • Product descriptionBisindolylmaleimide I 98+%
  • Packaging1g
  • Price$4335
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000052
  • Product descriptionBISINDOLYLMALEIMIDE (I) 95.00%
  • Packaging1MG
  • Price$708.48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000052
  • Product descriptionBISINDOLYLMALEIMIDE (I) 95.00%
  • Packaging5MG
  • Price$986.15
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8342
  • Product descriptionGF 109203X
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8342
  • Product descriptionGF 109203X
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8342
  • Product descriptionGF 109203X
  • Packaging10mM(in 1mL DMSO)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8342
  • Product descriptionGF 109203X
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60111
  • Product descriptionBisindolylmaleimideI(GF109203X)
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0009-M001 Bisindolylmaleimide I ≥97%(NMR) 1mg $55 2021-12-16 Buy
AK Scientific 1641AH Bisindolylmaleimide I 1mg $100 2021-12-16 Buy
Alfa Aesar J63401 Bisindolylmaleimide 1 5mg $153.65 2024-03-01 Buy
Alfa Aesar J63401 Bisindolylmaleimide 1 25mg $421.65 2024-03-01 Buy
Ambeed A439059 Bisindolylmaleimide I 98+% 5mg $96 2021-12-16 Buy
Ambeed A439059 Bisindolylmaleimide I 98+% 25mg $230 2021-12-16 Buy
Ambeed A439059 Bisindolylmaleimide I 98+% 50mg $340 2021-12-16 Buy
Ambeed A439059 Bisindolylmaleimide I 98+% 100mg $510 2021-12-16 Buy
Ambeed A439059 Bisindolylmaleimide I 98+% 1g $4335 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000052 BISINDOLYLMALEIMIDE (I) 95.00% 1MG $708.48 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000052 BISINDOLYLMALEIMIDE (I) 95.00% 5MG $986.15 2021-12-16 Buy
ApexBio Technology A8342 GF 109203X 1unit $28 2021-12-16 Buy
ApexBio Technology A8342 GF 109203X 5mg $60 2021-12-16 Buy
ApexBio Technology A8342 GF 109203X 10mM(in 1mL DMSO) $100 2021-12-16 Buy
ApexBio Technology A8342 GF 109203X 10mg $120 2021-12-16 Buy
Arctom CFN60111 BisindolylmaleimideI(GF109203X) 10mg $288 2021-12-16 Buy

Properties

Melting point :280℃ (decomposition)
Boiling point :685.6±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~1 mg/mlsoluble
form :Liquid
pka :8.13±0.60(Predicted)
color :Orange
Water Solubility :Insoluble in water.
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine. It acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKCα-, β1-, β2-, γ-, δ-, and ε-isozymes. BIM I directly inhibits GSK3 in primary adipocyte lysates (IC50 = 360 nM) and in GSK3β immunoprecipitates derived from rat epididymal adipocytes (IC50 = 170 nM). This compound also competitively antagonizes the 5-HT3 receptor with a Ki value of 61 nM.

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