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ChemicalBook >> CAS DataBase List >> (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester price.
  • $23 - $5600
  • Product name: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
  • CAS: 149809-43-8
  • MF: C21H21F2N3O4S
  • MW: 449.47
  • EINECS:1308068-626-2
  • MDL Number:MFCD13195567
  • Synonyms:Posaconazole InterMediate;Posaconazole Main Ring;(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate;Posaconazole int1;Posaconazole Intermediate1;Posa-12 ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate;((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methyl;(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
Price39 Properties Safety Information Description
39 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Acrotein
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Ark Pharm
  • Chemenu
  • Chem-Impex
  • Crysdot
  • Labseeker
  • Matrix Scientific
  • Synthonix
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5MG
  • 10MG
  • 100mg
  • 200MG
  • 250mg
  • 500mg
  • 1.00g
  • 1g
  • 5g
  • 5.00g
  • 25g
  • 25.00g
  • 1000g
  • Manufactureraablocks
  • Product numberAA001LYD
  • Product description(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98%
  • Packaging1g
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001LYD
  • Product description(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98%
  • Packaging5g
  • Price$76
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001LYD
  • Product description(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 95%
  • Packaging25g
  • Price$360
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT99103
  • Product description(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester 95%
  • Packaging25G
  • Price$285
  • Updated2026-05-27
  • Buy
  • ManufacturerAcrotein
  • Product numberdm-2613
  • Product description(3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98%
  • Packaging25g
  • Price$313.6
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberdm-2613
  • Product description(3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98%
  • Packaging1g
  • Price$28.7
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberdm-2613
  • Product description(3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98%
  • Packaging5g
  • Price$93.1
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ3480
  • Product description(5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester
  • Packaging250mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ3480
  • Product description(5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester
  • Packaging100mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ96388
  • Product description(5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester
  • Packaging1g
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149809438
  • Product description((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate
  • Packaging5g
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149809438
  • Product description((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate
  • Packaging1g
  • Price$178.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0029265
  • Product description(5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00%
  • Packaging10MG
  • Price$691.27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0029265
  • Product description(5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00%
  • Packaging100MG
  • Price$1709.98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPN0002083
  • Product description(5R-CIS)-TOLUENE-4-SULFONIC ACID-5-(2,4-DIFLUOROPHENYL)-5-[1,2,4]TRIAZOL-1-YLMETHYLTETRAHYDROFURAN-3-YL-METHYL ESTER 95.00%
  • Packaging5MG
  • Price$497.48
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000097815
  • Product description((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate 97%
  • Packaging5g
  • Price$553
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001LYD (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98% 1g $23 2026-05-28 Buy
aablocks AA001LYD (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98% 5g $76 2026-05-28 Buy
aablocks AA001LYD (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 95% 25g $360 2026-05-28 Buy
ACHEMBLOCK T99103 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester 95% 25G $285 2026-05-27 Buy
Acrotein dm-2613 (3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98% 25g $313.6 2026-05-25 Buy
Acrotein dm-2613 (3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98% 1g $28.7 2026-05-25 Buy
Acrotein dm-2613 (3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98% 5g $93.1 2026-05-25 Buy
AK Scientific Z3480 (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester 250mg $112 2021-12-16 Buy
AK Scientific Z3480 (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester 100mg $56 2021-12-16 Buy
AK Scientific J96388 (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester 1g $217 2021-12-16 Buy
Alichem 149809438 ((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate 5g $530 2021-12-16 Buy
Alichem 149809438 ((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate 1g $178.2 2021-12-16 Buy
American Custom Chemicals Corporation HCH0029265 (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00% 10MG $691.27 2021-12-16 Buy
American Custom Chemicals Corporation HCH0029265 (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00% 100MG $1709.98 2021-12-16 Buy
American Custom Chemicals Corporation APN0002083 (5R-CIS)-TOLUENE-4-SULFONIC ACID-5-(2,4-DIFLUOROPHENYL)-5-[1,2,4]TRIAZOL-1-YLMETHYLTETRAHYDROFURAN-3-YL-METHYL ESTER 95.00% 5MG $497.48 2021-12-16 Buy
Ark Pharm P000097815 ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate 97% 5g $553 2021-12-16 Buy
Next Last

Properties

Melting point :100-102°C
Boiling point :608.1±65.0 °C(Predicted)
Density :1.40
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :slightly sol. in Chloroform
form :powder to crystal
pka :2.75±0.10(Predicted)
color :White to Orange to Green
InChI :InChI=1S/C21H21F2N3O4S/c1-15-2-5-18(6-3-15)31(27,28)30-11-16-9-21(29-10-16,12-26-14-24-13-25-26)19-7-4-17(22)8-20(19)23/h2-8,13-14,16H,9-12H2,1H3/t16-,21-/m0/s1
InChIKey :DFWVLCJRFGIRAK-HRAATJIYSA-N
SMILES :C1[C@](CN2N=CN=C2)(C2C(F)=CC(F)=CC=2)OC[C@H]1COS(=O)(=O)C1C=CC(C)=CC=1
CAS DataBase Reference :149809-43-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P330 Rinse mouth.
P361 Remove/Take off immediately all contaminated clothing.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Posaconazole intermediate. Antifungal agent.

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Suppliers and manufacturers

Tianjin Liontec Biopharma Co.,Ltd. Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd Tianjin Chempharmatech Co.,Ltd. Chengdu Better Pharmaceutical Technology Co.,Ltd. INTERCHEMIE NANJING PHARMATECH CO., LTD Gansu HaoTian Chemical Technology Co., Ltd. Shaanxi Lvyuan Biomedical Co., Ltd Gansu Haotian PharmaTech Co.,Ltd. J & K SCIENTIFIC LTD. Chembest Research Laboratories Limited