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ChemicalBook >> CAS DataBase List >> N-BUTYLDEOXYNOJIRIMYCIN, HYDROCHLORIDE

N-BUTYLDEOXYNOJIRIMYCIN, HYDROCHLORIDE

N-BUTYLDEOXYNOJIRIMYCIN, HYDROCHLORIDE price.
  • $37 - $3000
  • Product name: N-BUTYLDEOXYNOJIRIMYCIN, HYDROCHLORIDE
  • CAS: 210110-90-0
  • MF: C10H22ClNO4
  • MW: 255.74
  • EINECS:
  • MDL Number:MFCD00269940
  • Synonyms:Miglustat, Hydrochloride;(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-,3,4,5-Piperidinetriol Hydrochloride;N-BUTYLDEOXYNOJIRIMYCIN HCL;N-BUTYLDEOXYNOJIRIMYCIN, HYDROCHLORIDE;N-BUTYL-DNJ, HCL;NB-DNJ, HCL;N-(N-BUTYL)DEOXYNOJIRIMYCIN, HYDROCHLORIDE;(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride
25 prices
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Brand
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 5mg
  • 10MG
  • 10
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmbeed
  • Product numberA968121
  • Product descriptionMiglustathydrochloride 98+%
  • Packaging25mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA968121
  • Product descriptionMiglustathydrochloride 98+%
  • Packaging50mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA968121
  • Product descriptionMiglustathydrochloride 98+%
  • Packaging100mg
  • Price$381
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA968121
  • Product descriptionMiglustathydrochloride 98+%
  • Packaging250mg
  • Price$647
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000292
  • Product descriptionN-BUTYLDEOXYNOJIRIMYCIN HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000292
  • Product descriptionN-BUTYLDEOXYNOJIRIMYCIN HYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3402
  • Product descriptionMiglustathydrochloride
  • Packaging10mg
  • Price$297
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04673
  • Product descriptionN-Butyldeoxynojirimycin HCl
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04673
  • Product descriptionN-Butyldeoxynojirimycin HCl
  • Packaging2mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04673
  • Product descriptionN-Butyldeoxynojirimycin HCl
  • Packaging5mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04673
  • Product descriptionN-Butyldeoxynojirimycin HCl
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04673
  • Product descriptionN-Butyldeoxynojirimycin HCl
  • Packaging25mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21065
  • Product descriptionN-Butyldeoxynojirimycin (hydrochloride) ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21065
  • Product descriptionN-Butyldeoxynojirimycin (hydrochloride) ≥98%
  • Packaging5mg
  • Price$98
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21065
  • Product descriptionN-Butyldeoxynojirimycin (hydrochloride) ≥98%
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21065
  • Product descriptionN-Butyldeoxynojirimycin (hydrochloride) ≥98%
  • Packaging25mg
  • Price$353
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A968121 Miglustathydrochloride 98+% 25mg $170 2021-12-16 Buy
Ambeed A968121 Miglustathydrochloride 98+% 50mg $254 2021-12-16 Buy
Ambeed A968121 Miglustathydrochloride 98+% 100mg $381 2021-12-16 Buy
Ambeed A968121 Miglustathydrochloride 98+% 250mg $647 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000292 N-BUTYLDEOXYNOJIRIMYCIN HYDROCHLORIDE 95.00% 10MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000292 N-BUTYLDEOXYNOJIRIMYCIN HYDROCHLORIDE 95.00% 100MG $1686.3 2021-12-16 Buy
ApexBio Technology B3402 Miglustathydrochloride 10mg $297 2021-12-16 Buy
Biosynth Carbosynth MB04673 N-Butyldeoxynojirimycin HCl 1mg $50 2021-12-16 Buy
Biosynth Carbosynth MB04673 N-Butyldeoxynojirimycin HCl 2mg $80 2021-12-16 Buy
Biosynth Carbosynth MB04673 N-Butyldeoxynojirimycin HCl 5mg $125 2021-12-16 Buy
Biosynth Carbosynth MB04673 N-Butyldeoxynojirimycin HCl 10mg $200 2021-12-16 Buy
Biosynth Carbosynth MB04673 N-Butyldeoxynojirimycin HCl 25mg $450 2021-12-16 Buy
Cayman Chemical 21065 N-Butyldeoxynojirimycin (hydrochloride) ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 21065 N-Butyldeoxynojirimycin (hydrochloride) ≥98% 5mg $98 2024-03-01 Buy
Cayman Chemical 21065 N-Butyldeoxynojirimycin (hydrochloride) ≥98% 10mg $161 2024-03-01 Buy
Cayman Chemical 21065 N-Butyldeoxynojirimycin (hydrochloride) ≥98% 25mg $353 2024-03-01 Buy

Properties

Melting point :169-172°C
storage temp. :Inert atmosphere,Room Temperature
solubility :Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml)
form :White to off-white solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-ButyldeoxynojirimycinHCl is a novel inhibitor of UGCG (glucosylceramide synthase) as well as Glucosidase I and II (α-glucosidase I and II). The compound has been shown to inhibit glucosylceramide synthase without ceramide accumulation and cell death. When administered to young mice the compound reduced glycosphingolipid production 50%-70% in the liver and lymphoid organs without any overt pathology. It is a potent inhibitor of HIV virus replication and syncytium formation in vitro. The compound has been observed to restore cAMP-activated chloride currents in epithelial cystic fibrosis cells through prevented interaction among calnexin and delF508-CFTR. In a mice model for Tay Sachs disease, mice exposed to N-ButyldeoxynojirimycinHCl limited the biosynthesis of GM2 thus preventing accumulation of GM2 in the brain and glycosphingolipids. This action markedly reduced the number of storage neurons and gangliosides per cell. N-ButyldeoxynojirimycinHCl has also rescued trafficking-deficient F508del-CTFR in human airway epithelial cells via inhibition of ER-glucosidases I and II. Also has broad spectrum antiviral activity.