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ChemicalBook >> CAS DataBase List >> 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid

4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid

4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid price.
  • $49 - $2400
  • Product name: 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid
  • CAS: 215030-90-3
  • MF: C29H24O2
  • MW: 404.5
  • EINECS:
  • MDL Number:MFCD17215944
  • Synonyms:4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid;BMS 493;(E)-4-[2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)naphthalen-2-yl]ethen-1-yl]benzoic acid;4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(phenylethynyl)-2-naphthalenyl]ethenyl]-benzoic acid;BMS204, 493;Benzoic acid, 4-[(1E)-2-[5,6-dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]-;(E)-4-(2-(5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl)vinyl)benzoic acid;BMS493,BMS-493
Price41 Properties Safety Information Description
41 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mlx10mM(inDMSO)
  • 2mg
  • 2.5mg
  • 1mg
  • 50
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1g
  • 250mg
  • 10mM*1mLinDMSO(Solution)
  • Manufactureraablocks
  • Product numberAA0070YS
  • Product descriptionBMS493 ≥98%
  • Packaging1mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070YS
  • Product descriptionBMS493 ≥98%
  • Packaging5mg
  • Price$120
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070YS
  • Product descriptionBMS493 ≥98%
  • Packaging25mg
  • Price$469
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070YS
  • Product descriptionBMS493 ≥98%
  • Packaging10mg
  • Price$213
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD264254
  • Product descriptionBMS493 98%
  • Packaging5MG
  • Price$125
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD264254
  • Product descriptionBMS493 98%
  • Packaging25MG
  • Price$475
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number4149CR
  • Product description4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid
  • Packaging10mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4149CR
  • Product description4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid
  • Packaging25mg
  • Price$572
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7415
  • Product descriptionBMS 493
  • Packaging5mg
  • Price$108
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7415
  • Product descriptionBMS 493
  • Packaging25mg
  • Price$298
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7415
  • Product descriptionBMS 493
  • Packaging10mg
  • Price$203
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-108529
  • Product descriptionBMS493 99.14%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$93
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-108529
  • Product descriptionBMS493 99.14%
  • Packaging5mg
  • Price$84
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-108529
  • Product descriptionBMS493 99.14%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$88
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-108529
  • Product descriptionBMS493 99.14%
  • Packaging10mg
  • Price$157
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-108529
  • Product descriptionBMS493 99.14%
  • Packaging25mg
  • Price$314
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0070YS BMS493 ≥98% 1mg $49 2026-05-28 Buy
aablocks AA0070YS BMS493 ≥98% 5mg $120 2026-05-28 Buy
aablocks AA0070YS BMS493 ≥98% 25mg $469 2026-05-28 Buy
aablocks AA0070YS BMS493 ≥98% 10mg $213 2026-05-28 Buy
ACHEMBLOCK AD264254 BMS493 98% 5MG $125 2026-05-27 Buy
ACHEMBLOCK AD264254 BMS493 98% 25MG $475 2026-05-27 Buy
AK Scientific 4149CR 4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid 10mg $313 2021-12-16 Buy
AK Scientific 4149CR 4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid 25mg $572 2021-12-16 Buy
ApexBio Technology B7415 BMS 493 5mg $108 2026-05-06 Buy
ApexBio Technology B7415 BMS 493 25mg $298 2026-05-06 Buy
ApexBio Technology B7415 BMS 493 10mg $203 2026-05-06 Buy
Arctom HY-108529 BMS493 99.14% 10mM*1mLinDMSO(Solution) $93 2026-05-26 Buy
Arctom HY-108529 BMS493 99.14% 5mg $84 2026-05-26 Buy
Arctom HY-108529 BMS493 99.14% 10mM*1mLinDMSO(Solid+Solvent) $88 2026-05-26 Buy
Arctom HY-108529 BMS493 99.14% 10mg $157 2026-05-26 Buy
Arctom HY-108529 BMS493 99.14% 25mg $314 2026-05-26 Buy
Next Last

Properties

Boiling point :605.4±55.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :4.27±0.10(Predicted)
form :powder
color :light yellow to yellow
InChI :1S/C29H24O2/c1-29(2)19-18-24(14-10-21-6-4-3-5-7-21)26-20-23(13-17-27(26)29)9-8-22-11-15-25(16-12-22)28(30)31/h3-9,11-13,15-18,20H,19H2,1-2H3,(H,30,31)/b9-8+
InChIKey :YCADIXLLWMXYKW-CMDGGOBGSA-N
SMILES :CC1(C)CC=C(C#Cc2ccccc2)c3cc(\C=C\c4ccc(cc4)C(O)=O)ccc13

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:

Description

Nuclear retinoic acid receptors (RARs) are transcriptional regulators with roles in cell proliferation and differentiation. BMS 493 is a pan-RAR inverse agonist that blocks RARα activity with an IC50 value of 114 nM. In all RAR types (RARα, RARβ, and RARγ), BMS493 prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions. BMS 493 has been used to elucidate the critical roles of RARs in development and immune response.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
BMS493
BMS493 CAS:215030-90-3
3B Pharmachem (Wuhan) International Co.,Ltd. Sigma-Aldrich Shanghai Beckham Medical Technology Co., Ltd EMMX Biotechnology LLC BOC Sciences Beijing Solarbio Science & Tecnology Co., Ltd. Aikon International Limited BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd.