22(R)-HYDROXYCHOLESTEROL
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- $61 - $1963.5
- Product name: 22(R)-HYDROXYCHOLESTEROL
- CAS: 17954-98-2
- MF: C27H46O2
- MW: 402.65
- EINECS:
- MDL Number:MFCD00070042
- Synonyms:22α-Hydroxycholesterol, 5-Cholestene-3β,22(R)-diol, 5-Cholestene-3β,22[R]-diol;(22R)-Cholest-5-ene-3β,22-diol;22R-OHC;(3beta,22R)-Cholest-5-ene-3,22-diol;Cholest-5-ene-3,22-diol, (3beta,22R)-;(20S,22R)-Cholest-5-ene-3β,22-diol;(3β,22R)-Cholest-5-ene-3,22-diol;Cholest-5-ene-3β,22(R)-diol
11 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10MG
- 25mg
- 100MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020765
- Product description22-(R)-HYDROXYCHOLESTEROL 95.00%
- Packaging10MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020765
- Product description22-(R)-HYDROXYCHOLESTEROL 95.00%
- Packaging100MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3151
- Product description22(R)-hydroxyCholesterol
- Packaging1mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3151
- Product description22(R)-hydroxyCholesterol
- Packaging5mg
- Price$299
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3151
- Product description22(R)-hydroxyCholesterol
- Packaging10mg
- Price$532
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number89355
- Product description22(R)-hydroxy Cholesterol ≥98%
- Packaging1mg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number89355
- Product description22(R)-hydroxy Cholesterol ≥98%
- Packaging5mg
- Price$264
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number89355
- Product description22(R)-hydroxy Cholesterol ≥98%
- Packaging10mg
- Price$468
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberH9384
- Product description22(R)-Hydroxycholesterol ≥98%
- Packaging1mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberH9384
- Product description22(R)-Hydroxycholesterol ≥98%
- Packaging5mg
- Price$418
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberH918015
- Product description22α-HydroxyCholesterol
- Packaging25mg
- Price$1135
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | LIP0020765 | 22-(R)-HYDROXYCHOLESTEROL 95.00% | 10MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0020765 | 22-(R)-HYDROXYCHOLESTEROL 95.00% | 100MG | $1963.5 | 2021-12-16 | Buy |
| ApexBio Technology | C3151 | 22(R)-hydroxyCholesterol | 1mg | $67 | 2021-12-16 | Buy |
| ApexBio Technology | C3151 | 22(R)-hydroxyCholesterol | 5mg | $299 | 2021-12-16 | Buy |
| ApexBio Technology | C3151 | 22(R)-hydroxyCholesterol | 10mg | $532 | 2021-12-16 | Buy |
| Cayman Chemical | 89355 | 22(R)-hydroxy Cholesterol ≥98% | 1mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 89355 | 22(R)-hydroxy Cholesterol ≥98% | 5mg | $264 | 2024-03-01 | Buy |
| Cayman Chemical | 89355 | 22(R)-hydroxy Cholesterol ≥98% | 10mg | $468 | 2024-03-01 | Buy |
| Sigma-Aldrich | H9384 | 22(R)-Hydroxycholesterol ≥98% | 1mg | $110 | 2024-03-01 | Buy |
| Sigma-Aldrich | H9384 | 22(R)-Hydroxycholesterol ≥98% | 5mg | $418 | 2024-03-01 | Buy |
| TRC | H918015 | 22α-HydroxyCholesterol | 25mg | $1135 | 2021-12-16 | Buy |
Properties
Melting point :171-174°C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :15.01±0.20(Predicted)
color :White to Off-White
InChIKey :RZPAXNJLEKLXNO-QUOSNDFLSA-N
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :15.01±0.20(Predicted)
color :White to Off-White
InChIKey :RZPAXNJLEKLXNO-QUOSNDFLSA-N
Safety Information
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Description
The liver X receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands are oxysterols. LXRs regulate the oxysterol-induced expression of cholesterol 7α-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. 22(R)-hydroxy Cholesterol is an endogenous agonist for LXRs that activates LXRα with an EC50 value of 325 nM. 22(R)-hydroxy Cholesterol, acting through LXR heterodimerized with the retinoid X receptor, induces the expression of the ABCA1 reverse cholesterol transporter. This activity increases the efflux of cholesterol from enterocytes and thus inhibits the overall absorption of cholesterol. 22(R)-hydroxy Cholesterol can be used as a substrate to monitor cholesterol transport or as an endogenous positive control for testing LXR agonists which have potential as therapeutic agents for the treatment of atherosclerosis.Related product price
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