22(R)-hydroxy Cholesterol
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- $68 - $3120
- Product name: 22(R)-hydroxy Cholesterol
- CAS: 17954-98-2
- MF: C27H46O2
- MW: 402.65
- EINECS:
- MDL Number:MFCD00070042
- Synonyms:22α-Hydroxycholesterol, 5-Cholestene-3β,22(R)-diol, 5-Cholestene-3β,22[R]-diol;(22R)-Cholest-5-ene-3β,22-diol;22R-OHC;(3beta,22R)-Cholest-5-ene-3,22-diol;Cholest-5-ene-3,22-diol, (3beta,22R)-;(20S,22R)-Cholest-5-ene-3β,22-diol;(3β,22R)-Cholest-5-ene-3,22-diol;Cholest-5-ene-3β,22(R)-diol
31 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 10mM*1mLinEthanol(Solution)
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25MG
- 100MG
- Manufactureraablocks
- Product numberAA00270C
- Product description(8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol ≥98%
- Packaging1mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00270C
- Product description(8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol ≥98%
- Packaging5mg
- Price$291
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00270C
- Product description(8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol ≥98%
- Packaging10mg
- Price$515
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD253008
- Product description22(R)-Hydroxycholesterol 98%
- Packaging5MG
- Price$1040
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD253008
- Product description22(R)-Hydroxycholesterol 98%
- Packaging25MG
- Price$3120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD253008
- Product description22(R)-Hydroxycholesterol 98%
- Packaging1MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020765
- Product description22-(R)-HYDROXYCHOLESTEROL 95.00%
- Packaging10MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020765
- Product description22-(R)-HYDROXYCHOLESTEROL 95.00%
- Packaging100MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3151
- Product description22(R)-hydroxy Cholesterol
- Packaging5mg
- Price$399
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3151
- Product description22(R)-hydroxy Cholesterol
- Packaging1mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3151
- Product description22(R)-hydroxy Cholesterol
- Packaging10mg
- Price$710
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-116969
- Product description22(R)-Hydroxycholesterol 99.86%
- Packaging1mg
- Price$73
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116969
- Product description22(R)-Hydroxycholesterol 99.86%
- Packaging10mM*1mLinEthanol(Solution)
- Price$314
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116969
- Product description22(R)-Hydroxycholesterol 99.86%
- Packaging5mg
- Price$285
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116969
- Product description22(R)-Hydroxycholesterol 99.86%
- Packaging10mg
- Price$494
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberFH23942
- Product description22α-Hydroxy cholesterol
- Packaging1mg
- Price$324.5
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00270C | (8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol ≥98% | 1mg | $68 | 2026-05-28 | Buy |
| aablocks | AA00270C | (8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol ≥98% | 5mg | $291 | 2026-05-28 | Buy |
| aablocks | AA00270C | (8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol ≥98% | 10mg | $515 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD253008 | 22(R)-Hydroxycholesterol 98% | 5MG | $1040 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD253008 | 22(R)-Hydroxycholesterol 98% | 25MG | $3120 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD253008 | 22(R)-Hydroxycholesterol 98% | 1MG | $295 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | LIP0020765 | 22-(R)-HYDROXYCHOLESTEROL 95.00% | 10MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0020765 | 22-(R)-HYDROXYCHOLESTEROL 95.00% | 100MG | $1963.5 | 2021-12-16 | Buy |
| ApexBio Technology | C3151 | 22(R)-hydroxy Cholesterol | 5mg | $399 | 2026-05-06 | Buy |
| ApexBio Technology | C3151 | 22(R)-hydroxy Cholesterol | 1mg | $90 | 2026-05-06 | Buy |
| ApexBio Technology | C3151 | 22(R)-hydroxy Cholesterol | 10mg | $710 | 2026-05-06 | Buy |
| Arctom | HY-116969 | 22(R)-Hydroxycholesterol 99.86% | 1mg | $73 | 2026-05-26 | Buy |
| Arctom | HY-116969 | 22(R)-Hydroxycholesterol 99.86% | 10mM*1mLinEthanol(Solution) | $314 | 2026-05-26 | Buy |
| Arctom | HY-116969 | 22(R)-Hydroxycholesterol 99.86% | 5mg | $285 | 2026-05-26 | Buy |
| Arctom | HY-116969 | 22(R)-Hydroxycholesterol 99.86% | 10mg | $494 | 2026-05-26 | Buy |
| Biosynth | FH23942 | 22α-Hydroxy cholesterol | 1mg | $324.5 | 2026-06-04 | Buy |
Properties
Melting point :171-174°C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :15.01±0.20(Predicted)
color :White to Off-White
InChIKey :RZPAXNJLEKLXNO-QUOSNDFLSA-N
SMILES :[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)[C@H](O)CCC(C)C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :15.01±0.20(Predicted)
color :White to Off-White
InChIKey :RZPAXNJLEKLXNO-QUOSNDFLSA-N
SMILES :[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)[C@H](O)CCC(C)C
Safety Information
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Description
The liver X receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands are oxysterols. LXRs regulate the oxysterol-induced expression of cholesterol 7α-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. 22(R)-hydroxy Cholesterol is an endogenous agonist for LXRs that activates LXRα with an EC50 value of 325 nM. 22(R)-hydroxy Cholesterol, acting through LXR heterodimerized with the retinoid X receptor, induces the expression of the ABCA1 reverse cholesterol transporter. This activity increases the efflux of cholesterol from enterocytes and thus inhibits the overall absorption of cholesterol. 22(R)-hydroxy Cholesterol can be used as a substrate to monitor cholesterol transport or as an endogenous positive control for testing LXR agonists which have potential as therapeutic agents for the treatment of atherosclerosis.Related product price
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Sigma-Aldrich
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