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ChemicalBook >> CAS DataBase List >> L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-

L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-

L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- price.
  • $180 - $1300
  • Product name: L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-
  • CAS: 2410-93-7
  • MF: C20H21N7O6
  • MW: 455.42
  • EINECS:
  • MDL Number:
  • Synonyms:Methotrexate Related CoMpound C;L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-;N(10)-methylfolate;10-Methylpteroylglutamic acid;N-[4-[[(2-Amino-4-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid;N-[4-[Methyl(2-amino-4-hydroxypteridine-6-ylmethyl)amino]benzoyl]glutamic acid;N-[p-[[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino]benzoyl]-L-glutamic acid;N10-Methylfolic acid
Price5 Properties Safety Information Description
5 prices
Selected condition：
Brand
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 100mg
  • 10 mg
  • 50mg
  • y0000663
  • ManufacturerMedical Isotopes, Inc.
  • Product number60106
  • Product descriptionMethopterine
  • Packaging100mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0000663
  • Product descriptionMethotrexate impurity C European Pharmacopoeia (EP) Reference Standard
  • Packagingy0000663
  • Price$220
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0000663
  • Product descriptionMethotrexate impurity C European Pharmacopoeia (EP) Reference Standard
  • Packaging10 mg
  • Price$236
  • Updated2025-07-31
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1414036
  • Product descriptionMethotrexate impurity C
  • Packaging50mg
  • Price$1300
  • Updated2025-07-31
  • Buy
  • ManufacturerTRC
  • Product numberM305370
  • Product descriptionMethopterine
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Medical Isotopes, Inc. 60106 Methopterine 100mg $390 2021-12-16 Buy
Sigma-Aldrich Y0000663 Methotrexate impurity C European Pharmacopoeia (EP) Reference Standard y0000663 $220 2024-03-01 Buy
Sigma-Aldrich Y0000663 Methotrexate impurity C European Pharmacopoeia (EP) Reference Standard 10 mg $236 2025-07-31 Buy
Sigma-Aldrich 1414036 Methotrexate impurity C 50mg $1300 2025-07-31 Buy
TRC M305370 Methopterine 100mg $180 2021-12-16 Buy

Properties

Melting point :144 - 150°C
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMF (Slightly, Heated), DMSO (Slightly)
pka :3.49±0.10(Predicted)
color :Pale Brown to Brown
Major Application :pharmaceutical (small molecule)
InChIKey :HLIXOCXUWGDBNP-UHFFFAOYSA-N
SMILES :N(Cc2nc3c(nc(nc3O)N)nc2)(C)c1ccc(cc1)C(=O)NC(CCC(=O)O)C(=O)O

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.

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