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ChemicalBook >> CAS DataBase List >> Levobupivacaine hydrochloride

Levobupivacaine hydrochloride

Levobupivacaine hydrochloride price.
  • $37 - $1504.5
  • Product name: Levobupivacaine hydrochloride
  • CAS: 27262-48-2
  • MF: C18H29ClN2O
  • MW: 324.89
  • EINECS:1308068-626-2
  • MDL Number:MFCD01704265
  • Synonyms:TIMTEC-BB SBB001337;(S)-(-)-BUPIVACAINE HCL;(S)-(-)-BUPIVACAINE HYDROCHLORIDE;(S)-(-)-1-N-BUTYL-2',6'-DIMETHYL-2-PIPERIDINCARBOXANILID HYDROCHLORIDE;(S)-(-)-1-BUTYL-2-(2,6-XYLYLCARBAMOYL)-PIPERIDINE HYDROCHLORIDE;s-(-)-1-butyl-2',6'-pipecoloxylidide hydrochloride;(s)-1-butyl-2’,6’-piperidinecarboxamidemonohydrochloride ;(s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride
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  • AK Scientific
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  • 10mM*1mLinDMSO(Solid+Solvent)
  • ManufacturerAK Scientific
  • Product numberN768
  • Product descriptionLevobupivacaineHCl
  • Packaging1g
  • Price$95
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003158
  • Product descriptionLEVOBUPIVACAINE HYDROCHLORIDE 95.00%
  • Packaging50MG
  • Price$224.7
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003158
  • Product descriptionLEVOBUPIVACAINE HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$1443.75
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1784
  • Product descriptionLevobupivacaine HCl
  • Packaging10mM(in1mLDMSO)
  • Price$50
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB1784
  • Product descriptionLevobupivacaine HCl
  • Packaging50mg
  • Price$68
  • Updated2026-05-06
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging25mg
  • Price$72
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging50mg
  • Price$80
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging10mg
  • Price$57
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging5mg
  • Price$37
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$38
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$39
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging100mg
  • Price$103
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging200mg
  • Price$137
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0653A
  • Product descriptionLevobupivacaine hydrochloride 99.86%
  • Packaging500mg
  • Price$217
  • Updated2026-05-26
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  • ManufacturerAvaChem
  • Product number2871
  • Product descriptionLevobupivacaine Hydrochloride
  • Packaging1g
  • Price$95
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2871
  • Product descriptionLevobupivacaine Hydrochloride
  • Packaging1g
  • Price$95
  • Updated2026-05-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific N768 LevobupivacaineHCl 1g $95 2021-12-16 Buy
American Custom Chemicals Corporation API0003158 LEVOBUPIVACAINE HYDROCHLORIDE 95.00% 50MG $224.7 2021-12-16 Buy
American Custom Chemicals Corporation API0003158 LEVOBUPIVACAINE HYDROCHLORIDE 95.00% 1G $1443.75 2021-12-16 Buy
ApexBio Technology B1784 Levobupivacaine HCl 10mM(in1mLDMSO) $50 2026-05-06 Buy
ApexBio Technology B1784 Levobupivacaine HCl 50mg $68 2026-05-06 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 25mg $72 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 50mg $80 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 10mg $57 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 5mg $37 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 10mM*1mLinDMSO(Solid+Solvent) $38 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 10mM*1mLinDMSO(Solution) $39 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 100mg $103 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 200mg $137 2026-05-26 Buy
Arctom HY-B0653A Levobupivacaine hydrochloride 99.86% 500mg $217 2026-05-26 Buy
AvaChem 2871 Levobupivacaine Hydrochloride 1g $95 2021-12-16 Buy
AvaChem 2871 Levobupivacaine Hydrochloride 1g $95 2026-05-22 Buy

Properties

Melting point :254 °C (dec.)(lit.)
alpha :-12.5 º (c=2, water)
storage temp. :2-8°C
solubility :H2O: soluble20mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D -10 to -14°, c = 1.0 in H2O
Water Solubility :H2O: 20mg/mL, clear
InChI :InChI=1/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H/t16-;/s3
InChIKey :SIEYLFHKZGLBNX-NTISSMGPSA-N
SMILES :C([C@@H]1CCCCN1CCCC)(=O)NC1C(=CC=CC=1C)C.Cl |&1:1,r|
CAS DataBase Reference :27262-48-2(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Levobupivacaine was first launched in the US for the production of local anesthesia for surgery and obstetrics and for post-operative pain management. It is the (S)-enantiomer of the long acting, highly potent local anesthetic bupivacaine (Marcaine) that can be prepared by a three step sequence from (S)-pipecolic acid or from (S)-lysine by oxidative deamination and stereospecific ring closure to (S)-pipecolamide core structure. Levobupivacaine exhibits its long-acting local anesthetic effect by blocking neuronal sodium channel ion flow in nerve axons. Clinical studies demonstrated an efficacy and a general profile closely resembling those of the racemic bupivacaine currently in use; however, it produced an enhanced safety profile, in particular substantially reduced (about one-third) cardiotoxicity (less effect on myocardial contractility and QT, prolongation) and CNS depressive side effects. Onset and duration of blockade were also equivalent or even better.

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