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ChemicalBook >> CAS DataBase List >> Glycine, N-(3,5-dibroMo-4-Methylphenyl)-, 2-[(2-hydroxy-5-nitrophenyl)Methylene]hydrazide

Glycine, N-(3,5-dibroMo-4-Methylphenyl)-, 2-[(2-hydroxy-5-nitrophenyl)Methylene]hydrazide

Glycine, N-(3,5-dibroMo-4-Methylphenyl)-, 2-[(2-hydroxy-5-nitrophenyl)Methylene]hydrazide price.
16 prices
Selected condition:
Brand
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 2x5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAxon Medchem
  • Product numberAxon2549
  • Product descriptionL67 99%
  • Packaging2x5mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22941
  • Product descriptionL67 ≥98%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22941
  • Product descriptionL67 ≥98%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22941
  • Product descriptionL67 ≥98%
  • Packaging25mg
  • Price$433
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22941
  • Product descriptionL67 ≥98%
  • Packaging50mg
  • Price$721
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5279
  • Product descriptionL67 >98.0%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5279
  • Product descriptionL67 >98.0%
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5279
  • Product descriptionL67 >98.0%
  • Packaging50mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5279
  • Product descriptionL67 >98.0%
  • Packaging100mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002247
  • Product descriptionL67 98+%
  • Packaging5mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002247
  • Product descriptionL67 98+%
  • Packaging10mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002247
  • Product descriptionL67 98+%
  • Packaging50mg
  • Price$1050
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002247
  • Product descriptionL67 98+%
  • Packaging100mg
  • Price$1470
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8790
  • Product descriptionL67 >98%
  • Packaging100mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8790
  • Product descriptionL67 >98%
  • Packaging250mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8790
  • Product descriptionL67 >98%
  • Packaging1g
  • Price$1700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Axon Medchem Axon2549 L67 99% 2x5mg $154 2021-12-16 Buy
Cayman Chemical 22941 L67 ≥98% 5mg $97 2024-03-01 Buy
Cayman Chemical 22941 L67 ≥98% 10mg $184 2024-03-01 Buy
Cayman Chemical 22941 L67 ≥98% 25mg $433 2024-03-01 Buy
Cayman Chemical 22941 L67 ≥98% 50mg $721 2024-03-01 Buy
ChemScene CS-5279 L67 >98.0% 5mg $50 2021-12-16 Buy
ChemScene CS-5279 L67 >98.0% 10mg $80 2021-12-16 Buy
ChemScene CS-5279 L67 >98.0% 50mg $180 2021-12-16 Buy
ChemScene CS-5279 L67 >98.0% 100mg $280 2021-12-16 Buy
Crysdot CD31002247 L67 98+% 5mg $245 2021-12-16 Buy
Crysdot CD31002247 L67 98+% 10mg $350 2021-12-16 Buy
Crysdot CD31002247 L67 98+% 50mg $1050 2021-12-16 Buy
Crysdot CD31002247 L67 98+% 100mg $1470 2021-12-16 Buy
DC Chemicals DC8790 L67 >98% 100mg $420 2021-12-16 Buy
DC Chemicals DC8790 L67 >98% 250mg $800 2021-12-16 Buy
DC Chemicals DC8790 L67 >98% 1g $1700 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:21.5(Max Conc. mg/mL);44.23(Max Conc. mM)
DMF:10.0(Max Conc. mg/mL);20.57(Max Conc. mM)
Water:1.0(Max Conc. mg/mL);2.06(Max Conc. mM) form :A crystalline solid

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

L67 is a competitive inhibitor of DNA ligases I and III (IC50s = 10 and 10 μM for human DNA ligase I and human ligase IIIβ). It blocks DNA binding (Ki = 10 μM), increasing the cytotoxicity of DNA-damaging agents. It also inhibits mitochondrial DNA ligase IIIα and induces the production of reactive oxygen species (ROS) and apoptosis in cancerous, but not non-malignant, cells. It does not inhibit DNA ligase IV or T4 DNA ligase at concentrations up to 100 μM.