N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide
![N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide price.](/CAS/20200119/GIF/329198-87-0.gif)
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- $12 - $4741
- Product name: N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide
- CAS: 329198-87-0
- MF: C17H10N2O5
- MW: 322.27
- EINECS:-0
- MDL Number:
- Synonyms:N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide;C-178;N-(3-Dibenzofuranyl)-5-nitro-2-furancarboxamide;2-Furancarboxamide, N-3-dibenzofuranyl-5-nitro-;MITA,inhibit,Inhibitor,STING,MPYS,C178,ERIS,C-178,C 178,Stimulator of Interferon Genes,TMEM173;STING Antagonist (C-178);C-178, 10 mM in DMSO;STING inhibitor C-178 (C-178)
38 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- AvaChem
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 5G
- 10mM(1mLinDMSO)
- Manufactureraablocks
- Product numberAA01E439
- Product descriptionC-178 98%
- Packaging25mg
- Price$48
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E439
- Product descriptionC-178 ≥98%
- Packaging250mg
- Price$264
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E439
- Product descriptionC-178 ≥98%
- Packaging1g
- Price$672
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E439
- Product descriptionC-178 ≥98%
- Packaging10mg
- Price$26
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E439
- Product descriptionC-178 98%
- Packaging5mg
- Price$22
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E439
- Product descriptionC-178 98%
- Packaging1mg
- Price$12
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229198
- Product descriptionC-178 97.00%
- Packaging5G
- Price$920
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229198
- Product descriptionC-178 97.00%
- Packaging1G
- Price$230
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3619CJ
- Product descriptionSTINGinhibitorC-178
- Packaging10mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3619CJ
- Product descriptionSTINGinhibitorC-178
- Packaging5mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSLK-S6667
- Product descriptionSTING inhibitor C-178 99.57%
- Packaging100mg
- Price$1872
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S6667
- Product descriptionSTING inhibitor C-178 99.57%
- Packaging1g
- Price$4741
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S6667
- Product descriptionSTING inhibitor C-178 99.57%
- Packaging25mg
- Price$853
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S6667
- Product descriptionSTING inhibitor C-178 99.57%
- Packaging5mg
- Price$283
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S6667
- Product descriptionSTING inhibitor C-178 99.57%
- Packaging10mM(1mLinDMSO)
- Price$352
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S6667
- Product descriptionSTING inhibitor C-178 99.57%
- Packaging2mg
- Price$142
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E439 | C-178 98% | 25mg | $48 | 2026-05-30 | Buy |
| aablocks | AA01E439 | C-178 ≥98% | 250mg | $264 | 2026-05-30 | Buy |
| aablocks | AA01E439 | C-178 ≥98% | 1g | $672 | 2026-05-30 | Buy |
| aablocks | AA01E439 | C-178 ≥98% | 10mg | $26 | 2026-05-30 | Buy |
| aablocks | AA01E439 | C-178 98% | 5mg | $22 | 2026-05-30 | Buy |
| aablocks | AA01E439 | C-178 98% | 1mg | $12 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y229198 | C-178 97.00% | 5G | $920 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229198 | C-178 97.00% | 1G | $230 | 2026-05-27 | Buy |
| AK Scientific | 3619CJ | STINGinhibitorC-178 | 10mg | $164 | 2021-12-16 | Buy |
| AK Scientific | 3619CJ | STINGinhibitorC-178 | 5mg | $133 | 2021-12-16 | Buy |
| Arctom | SLK-S6667 | STING inhibitor C-178 99.57% | 100mg | $1872 | 2026-05-26 | Buy |
| Arctom | SLK-S6667 | STING inhibitor C-178 99.57% | 1g | $4741 | 2026-05-26 | Buy |
| Arctom | SLK-S6667 | STING inhibitor C-178 99.57% | 25mg | $853 | 2026-05-26 | Buy |
| Arctom | SLK-S6667 | STING inhibitor C-178 99.57% | 5mg | $283 | 2026-05-26 | Buy |
| Arctom | SLK-S6667 | STING inhibitor C-178 99.57% | 10mM(1mLinDMSO) | $352 | 2026-05-26 | Buy |
| Arctom | SLK-S6667 | STING inhibitor C-178 99.57% | 2mg | $142 | 2026-05-26 | Buy |
Properties
Melting point :>225°C (dec.)
Boiling point :448.3±35.0 °C(Predicted)
Density :1.506±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :11.35±0.43(Predicted)
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :URUVDCCYSJEGQQ-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC(OC3=C4C=CC=C3)=C4C=C2
Boiling point :448.3±35.0 °C(Predicted)
Density :1.506±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :11.35±0.43(Predicted)
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :URUVDCCYSJEGQQ-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC(OC3=C4C=CC=C3)=C4C=C2
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
C-178 is a covalent inhibitor of stimulator of interferon genes (STING). It binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. C-178 (0.01-1.25 μM) selectively reduces STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity in HEK293 cells. It also prevents increases in Ifnb1 expression in bone marrow-derived macrophages (BMDMs) induced by cyclic di-GMP , double-stranded DNA, and LPS when used at a concentration of 0.5 μM.Related product price
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