N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide
- $32 - $1190
- Product name: N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide
- CAS: 329198-87-0
- MF: C17H10N2O5
- MW: 322.27
- EINECS:-0
- MDL Number:
- Synonyms:N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide;C-178;N-(3-Dibenzofuranyl)-5-nitro-2-furancarboxamide;2-Furancarboxamide, N-3-dibenzofuranyl-5-nitro-;MITA,inhibit,Inhibitor,STING,MPYS,C178,ERIS,C-178,C 178,Stimulator of Interferon Genes,TMEM173
15 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3619CJ
- Product descriptionSTINGinhibitorC-178
- Packaging10mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3619CJ
- Product descriptionSTINGinhibitorC-178
- Packaging5mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25860
- Product descriptionC-178
- Packaging5mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25860
- Product descriptionC-178
- Packaging10mg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25860
- Product descriptionC-178
- Packaging25mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25860
- Product descriptionC-178
- Packaging50mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0087693
- Product descriptionC-178 99.90%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0087693
- Product descriptionC-178 99.90%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0087693
- Product descriptionC-178 99.90%
- Packaging25mg
- Price$295
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0087693
- Product descriptionC-178 99.90%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0087693
- Product descriptionC-178 99.90%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10959
- Product descriptionSTINGinhibitorC-178 >98%
- Packaging250mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML3098
- Product descriptionC-178 ≥98% (HPLC)
- Packaging25MG
- Price$359
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML3098
- Product descriptionC-178 ≥98% (HPLC)
- Packaging5MG
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberD417535
- Product descriptionN-(3-Dibenzofuranyl)-5-nitro-2-furancarboxamide
- Packaging1g
- Price$1190
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3619CJ | STINGinhibitorC-178 | 10mg | $164 | 2021-12-16 | Buy |
AK Scientific | 3619CJ | STINGinhibitorC-178 | 5mg | $133 | 2021-12-16 | Buy |
Cayman Chemical | 25860 | C-178 | 5mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 25860 | C-178 | 10mg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 25860 | C-178 | 25mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 25860 | C-178 | 50mg | $230 | 2024-03-01 | Buy |
ChemScene | CS-0087693 | C-178 99.90% | 5mg | $100 | 2021-12-16 | Buy |
ChemScene | CS-0087693 | C-178 99.90% | 10mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-0087693 | C-178 99.90% | 25mg | $295 | 2021-12-16 | Buy |
ChemScene | CS-0087693 | C-178 99.90% | 50mg | $450 | 2021-12-16 | Buy |
ChemScene | CS-0087693 | C-178 99.90% | 100mg | $650 | 2021-12-16 | Buy |
DC Chemicals | DC10959 | STINGinhibitorC-178 >98% | 250mg | $700 | 2021-12-16 | Buy |
Sigma-Aldrich | SML3098 | C-178 ≥98% (HPLC) | 25MG | $359 | 2024-03-01 | Buy |
Sigma-Aldrich | SML3098 | C-178 ≥98% (HPLC) | 5MG | $89 | 2024-03-01 | Buy |
TRC | D417535 | N-(3-Dibenzofuranyl)-5-nitro-2-furancarboxamide | 1g | $1190 | 2021-12-16 | Buy |
Properties
Melting point :>225°C (dec.)
Boiling point :448.3±35.0 °C(Predicted)
Density :1.506±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :11.35±0.43(Predicted)
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :448.3±35.0 °C(Predicted)
Density :1.506±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :11.35±0.43(Predicted)
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
C-178 is a covalent inhibitor of stimulator of interferon genes (STING). It binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. C-178 (0.01-1.25 μM) selectively reduces STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity in HEK293 cells. It also prevents increases in Ifnb1 expression in bone marrow-derived macrophages (BMDMs) induced by cyclic di-GMP , double-stranded DNA, and LPS when used at a concentration of 0.5 μM.Related product price
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