4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
![4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide price.](/CAS/GIF/36707-00-3.gif)
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- $34 - $4355
- Product name: 4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
- CAS: 36707-00-3
- MF: C13H15N5O6
- MW: 337.29
- EINECS:
- MDL Number:
- Synonyms:NSC 177223;4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide;4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide;API-1;API-1(NSC 177223);Pyrido[2,3-d]pyrimidine-6-carboxamide, 4-amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-;4-Amino-5-oxo-8-pentofuranosyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide;4-amino-8-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide
33 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Cayman Chemical
- Chemenu
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1 ≥98%
- Packaging1mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging5mg
- Price$122
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging10mg
- Price$195
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging25mg
- Price$337
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging50mg
- Price$494
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging100mg
- Price$683
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127711
- Product description4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98%
- Packaging25MG
- Price$475
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127711
- Product description4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98%
- Packaging5MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberBA3136
- Product descriptionAPI-1
- Packaging1mg
- Price$192
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging5mg
- Price$168
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging5mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging1mg
- Price$38
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging10mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging10mg
- Price$297
- Updated2026-04-30
- Buy
- ManufacturerChemenu
- Product numberCM360211
- Product description4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+
- Packaging10mg
- Price$1055
- Updated2026-05-20
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C98P | API-1 ≥98% | 1mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 5mg | $122 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 10mg | $195 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 25mg | $337 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 50mg | $494 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 100mg | $683 | 2026-05-28 | Buy |
| ACHEMBLOCK | U127711 | 4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98% | 25MG | $475 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127711 | 4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98% | 5MG | $150 | 2026-05-27 | Buy |
| ApexBio Technology | BA3136 | API-1 | 1mg | $192 | 2026-05-06 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 5mg | $168 | 2026-04-30 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 5mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 1mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 10mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 10mg | $297 | 2026-04-30 | Buy |
| Chemenu | CM360211 | 4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+ | 10mg | $1055 | 2026-05-20 | Buy |
Properties
storage temp. :Store at RT
solubility :DMF: slightly soluble; DMSO: 2 mg/ml
form :powder
color :white to beige
InChI :1S/C13H15N5O6/c14-10-6-7(20)4(11(15)23)1-18(12(6)17-3-16-10)13-9(22)8(21)5(2-19)24-13/h1,3,5,8-9,13,19,21-22H,2H2,(H2,15,23)(H2,14,16,17)/t5-,8-,9-,13-/m1/s1
InChIKey :SPBWHPXCWJLQRU-FITJORAGSA-N
SMILES :O=C1C(C(N)=O)=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=C1C(N)=NC=N3
solubility :DMF: slightly soluble; DMSO: 2 mg/ml
form :powder
color :white to beige
InChI :1S/C13H15N5O6/c14-10-6-7(20)4(11(15)23)1-18(12(6)17-3-16-10)13-9(22)8(21)5(2-19)24-13/h1,3,5,8-9,13,19,21-22H,2H2,(H2,15,23)(H2,14,16,17)/t5-,8-,9-,13-/m1/s1
InChIKey :SPBWHPXCWJLQRU-FITJORAGSA-N
SMILES :O=C1C(C(N)=O)=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=C1C(N)=NC=N3
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
NSC 177223 is a Akt/protein kinase B inhibitor. It binds to pleckstrin homologous domain of Akt and blocks Akt membrane translocation. Treatment of cancer cells with NSC 177223 results in inhibition of the kinase activities and induction of cell growth arrest and apoptosis selectively in human cancer cells that harbor constitutively activated Akt.Suppliers and manufacturers
Career Henan Chemica Co
InvivoChem
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
NANJING YINGWEN BIOTECHNOLOGY CO LTD
Amadis Chemical Company Limited
