4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
![4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide price.](/CAS/GIF/36707-00-3.gif)
|
- $38 - $4355
- Product name: 4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
- CAS: 36707-00-3
- MF: C13H15N5O6
- MW: 337.29
- EINECS:
- MDL Number:
- Synonyms:NSC 177223;4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide;4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide;API-1;API-1(NSC 177223);Pyrido[2,3-d]pyrimidine-6-carboxamide, 4-amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-;4-Amino-5-oxo-8-pentofuranosyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide;4-amino-8-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide
32 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 10mg
- 10
- 1mg
- 5mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1 ≥98%
- Packaging1mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging5mg
- Price$122
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging50mg
- Price$494
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging100mg
- Price$683
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging25mg
- Price$337
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C98P
- Product descriptionAPI-1
- Packaging10mg
- Price$195
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127711
- Product description4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98%
- Packaging5MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127711
- Product description4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98%
- Packaging25MG
- Price$475
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberBA3136
- Product descriptionAPI-1
- Packaging1mg
- Price$192
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging5mg
- Price$168
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging1mg
- Price$38
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number22081
- Product descriptionAPI-1 ≥98%
- Packaging10mg
- Price$297
- Updated2026-04-30
- Buy
- ManufacturerChemenu
- Product numberCM360211
- Product description4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+
- Packaging10mg
- Price$1055
- Updated2026-05-26
- Buy
- ManufacturerChemenu
- Product numberCM360211
- Product description4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+
- Packaging50mg
- Price$2823
- Updated2026-05-26
- Buy
- ManufacturerChemenu
- Product numberCM360211
- Product description4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+
- Packaging100mg
- Price$4355
- Updated2026-05-26
- Buy
- ManufacturerChemScene
- Product numberCS-0032919
- Product descriptionAPI-1 99.62%
- Packaging50mg
- Price$845
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C98P | API-1 ≥98% | 1mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 5mg | $122 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 50mg | $494 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 100mg | $683 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 25mg | $337 | 2026-05-28 | Buy |
| aablocks | AA00C98P | API-1 | 10mg | $195 | 2026-05-28 | Buy |
| ACHEMBLOCK | U127711 | 4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98% | 5MG | $150 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127711 | 4-amino-8-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 98% | 25MG | $475 | 2026-05-27 | Buy |
| ApexBio Technology | BA3136 | API-1 | 1mg | $192 | 2026-05-06 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 5mg | $168 | 2026-04-30 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 1mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 22081 | API-1 ≥98% | 10mg | $297 | 2026-04-30 | Buy |
| Chemenu | CM360211 | 4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+ | 10mg | $1055 | 2026-05-26 | Buy |
| Chemenu | CM360211 | 4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+ | 50mg | $2823 | 2026-05-26 | Buy |
| Chemenu | CM360211 | 4-amino-8-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 95%+ | 100mg | $4355 | 2026-05-26 | Buy |
| ChemScene | CS-0032919 | API-1 99.62% | 50mg | $845 | 2026-06-04 | Buy |
Properties
Boiling point :795.771±60.00 °C(Press: 760.00 Torr)(predicted)
Density :1.792±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :Store at RT
solubility :DMF: slightly soluble; DMSO: 2 mg/ml
form :powder
pka :12.077±0.20(predicted)
color :white to beige
InChI :1S/C13H15N5O6/c14-10-6-7(20)4(11(15)23)1-18(12(6)17-3-16-10)13-9(22)8(21)5(2-19)24-13/h1,3,5,8-9,13,19,21-22H,2H2,(H2,15,23)(H2,14,16,17)/t5-,8-,9-,13-/m1/s1
InChIKey :SPBWHPXCWJLQRU-FITJORAGSA-N
SMILES :O=C1C(C(N)=O)=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=C1C(N)=NC=N3
Density :1.792±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :Store at RT
solubility :DMF: slightly soluble; DMSO: 2 mg/ml
form :powder
pka :12.077±0.20(predicted)
color :white to beige
InChI :1S/C13H15N5O6/c14-10-6-7(20)4(11(15)23)1-18(12(6)17-3-16-10)13-9(22)8(21)5(2-19)24-13/h1,3,5,8-9,13,19,21-22H,2H2,(H2,15,23)(H2,14,16,17)/t5-,8-,9-,13-/m1/s1
InChIKey :SPBWHPXCWJLQRU-FITJORAGSA-N
SMILES :O=C1C(C(N)=O)=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=C1C(N)=NC=N3
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
NSC 177223 is a Akt/protein kinase B inhibitor. It binds to pleckstrin homologous domain of Akt and blocks Akt membrane translocation. Treatment of cancer cells with NSC 177223 results in inhibition of the kinase activities and induction of cell growth arrest and apoptosis selectively in human cancer cells that harbor constitutively activated Akt.Related product price
-
4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
$38-4355 -
Oridonin
$12-2567 -
SC 66
$15-1300
Suppliers and manufacturers
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
EMMX Biotechnology LLC
Pharmacodia (Beijing) Co.,Ltd
Shanghai EFE Biological Technology Co., Ltd.
Amadis Chemical Company Limited
Lynnchem
Novachemistry
Shenzhen Polymeri Biochemical Technology Co., Ltd.